Oral micro-electronic platform for temperature and humidity monitoring

Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature...

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Published in:Scientific Reports
Main Author: Popović Ž.V.; Thiha A.; Ibrahim F.; Petrović B.B.; Dahlan N.A.; Milić L.; Kojić S.; Stojanović G.M.
Format: Article
Language:English
Published: Nature Research 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178379547&doi=10.1038%2fs41598-023-48379-9&partnerID=40&md5=d32072b8dd7d0f5802dc90945da70445
id 2-s2.0-85178379547
spelling 2-s2.0-85178379547
Popović Ž.V.; Thiha A.; Ibrahim F.; Petrović B.B.; Dahlan N.A.; Milić L.; Kojić S.; Stojanović G.M.
Oral micro-electronic platform for temperature and humidity monitoring
2023
Scientific Reports
13
1
10.1038/s41598-023-48379-9
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178379547&doi=10.1038%2fs41598-023-48379-9&partnerID=40&md5=d32072b8dd7d0f5802dc90945da70445
Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature and humidity. This paper introduces the innovative Intra-Oral Portable Micro-Electronic (IOPM) fluidic theranostic device platform. It leverages conventional dental spoons by incorporating advanced sensors for precise measurements of oral temperature and humidity. Personalization options include a microfluidic chip and a tooth model, enabling targeted delivery of therapeutic agents to optimize treatment outcomes. The electronic control system simplifies the administration of fluid dosages, intelligently adjusted based on real-time oral cavity temperature and humidity readings. Rigorous experimental evaluations validate the platform’s precision in delivering fluid volumes at predefined intervals. This platform represents a transformative advancement for individuals contending with oral health challenges such as xerostomia (dry mouth). Furthermore, it has the potential to elevate oral healthcare standards by providing advanced diagnostics and tailored therapeutic solutions, benefiting both patients and dental professionals alike. © 2023, The Author(s).
Nature Research
20452322
English
Article
All Open Access; Gold Open Access
author Popović Ž.V.; Thiha A.; Ibrahim F.; Petrović B.B.; Dahlan N.A.; Milić L.; Kojić S.; Stojanović G.M.
spellingShingle Popović Ž.V.; Thiha A.; Ibrahim F.; Petrović B.B.; Dahlan N.A.; Milić L.; Kojić S.; Stojanović G.M.
Oral micro-electronic platform for temperature and humidity monitoring
author_facet Popović Ž.V.; Thiha A.; Ibrahim F.; Petrović B.B.; Dahlan N.A.; Milić L.; Kojić S.; Stojanović G.M.
author_sort Popović Ž.V.; Thiha A.; Ibrahim F.; Petrović B.B.; Dahlan N.A.; Milić L.; Kojić S.; Stojanović G.M.
title Oral micro-electronic platform for temperature and humidity monitoring
title_short Oral micro-electronic platform for temperature and humidity monitoring
title_full Oral micro-electronic platform for temperature and humidity monitoring
title_fullStr Oral micro-electronic platform for temperature and humidity monitoring
title_full_unstemmed Oral micro-electronic platform for temperature and humidity monitoring
title_sort Oral micro-electronic platform for temperature and humidity monitoring
publishDate 2023
container_title Scientific Reports
container_volume 13
container_issue 1
doi_str_mv 10.1038/s41598-023-48379-9
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178379547&doi=10.1038%2fs41598-023-48379-9&partnerID=40&md5=d32072b8dd7d0f5802dc90945da70445
description Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature and humidity. This paper introduces the innovative Intra-Oral Portable Micro-Electronic (IOPM) fluidic theranostic device platform. It leverages conventional dental spoons by incorporating advanced sensors for precise measurements of oral temperature and humidity. Personalization options include a microfluidic chip and a tooth model, enabling targeted delivery of therapeutic agents to optimize treatment outcomes. The electronic control system simplifies the administration of fluid dosages, intelligently adjusted based on real-time oral cavity temperature and humidity readings. Rigorous experimental evaluations validate the platform’s precision in delivering fluid volumes at predefined intervals. This platform represents a transformative advancement for individuals contending with oral health challenges such as xerostomia (dry mouth). Furthermore, it has the potential to elevate oral healthcare standards by providing advanced diagnostics and tailored therapeutic solutions, benefiting both patients and dental professionals alike. © 2023, The Author(s).
publisher Nature Research
issn 20452322
language English
format Article
accesstype All Open Access; Gold Open Access
record_format scopus
collection Scopus
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