Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans

The chemical composition of the essential oil of Lindera subumbelliflora (Lauraceae) was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterised by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The antifungal activity o...

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Published in:Natural Product Research
Main Author: Zaini N.N.M.; Salleh W.M.N.H.W.; Arzmi M.H.; Salihu A.S.; Ab Ghani N.
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175983773&doi=10.1080%2f14786419.2023.2278164&partnerID=40&md5=5d85ffe3fc271f3ec5790e755f80c9e2
id 2-s2.0-85175983773
spelling 2-s2.0-85175983773
Zaini N.N.M.; Salleh W.M.N.H.W.; Arzmi M.H.; Salihu A.S.; Ab Ghani N.
Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans
2023
Natural Product Research


10.1080/14786419.2023.2278164
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175983773&doi=10.1080%2f14786419.2023.2278164&partnerID=40&md5=5d85ffe3fc271f3ec5790e755f80c9e2
The chemical composition of the essential oil of Lindera subumbelliflora (Lauraceae) was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterised by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The antifungal activity of L. subumbelliflora essential oil was tested against Candida albicans and Streptococcus mutans using the broth microdilution assay, whereas the microbial biofilms were determined using a semi-quantitative static biofilm. A total of 28 components (99.6%) were successfully identified, which were characterised by β-eudesmol (14.6%), cis-α-bergamotene (11.0%), α-copaene (8.5%), dodecen-1-ol (8.5%), and (E)-nerolidol (8.3%). The essential oil exhibited activity against Candida albicans and Streptococcus mutans with MIC values of 250 and 500 µg/mL, respectively. The essential oil increased the biofilm of Candida albicans by 38.25%, however, decreased the biofilm of Streptococcus mutans by 47.89% when treated with 500 µg/mL. Thus, the essential oil has a promising application in dentistry via inhibition of the growth of Candida albicans and Streptococcus mutans. However, the antibiofilm activity of the essential oil is only applicable for cariogenic Streptococcus mutans. © 2023 Informa UK Limited, trading as Taylor & Francis Group.
Taylor and Francis Ltd.
14786419
English
Article
All Open Access; Green Open Access
author Zaini N.N.M.; Salleh W.M.N.H.W.; Arzmi M.H.; Salihu A.S.; Ab Ghani N.
spellingShingle Zaini N.N.M.; Salleh W.M.N.H.W.; Arzmi M.H.; Salihu A.S.; Ab Ghani N.
Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans
author_facet Zaini N.N.M.; Salleh W.M.N.H.W.; Arzmi M.H.; Salihu A.S.; Ab Ghani N.
author_sort Zaini N.N.M.; Salleh W.M.N.H.W.; Arzmi M.H.; Salihu A.S.; Ab Ghani N.
title Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans
title_short Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans
title_full Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans
title_fullStr Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans
title_full_unstemmed Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans
title_sort Chemical composition of essential oil from Lindera subumbelliflora Kosterm and its effect on the susceptibility and biofilm activities of Candida albicans and Streptococcus mutans
publishDate 2023
container_title Natural Product Research
container_volume
container_issue
doi_str_mv 10.1080/14786419.2023.2278164
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175983773&doi=10.1080%2f14786419.2023.2278164&partnerID=40&md5=5d85ffe3fc271f3ec5790e755f80c9e2
description The chemical composition of the essential oil of Lindera subumbelliflora (Lauraceae) was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterised by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The antifungal activity of L. subumbelliflora essential oil was tested against Candida albicans and Streptococcus mutans using the broth microdilution assay, whereas the microbial biofilms were determined using a semi-quantitative static biofilm. A total of 28 components (99.6%) were successfully identified, which were characterised by β-eudesmol (14.6%), cis-α-bergamotene (11.0%), α-copaene (8.5%), dodecen-1-ol (8.5%), and (E)-nerolidol (8.3%). The essential oil exhibited activity against Candida albicans and Streptococcus mutans with MIC values of 250 and 500 µg/mL, respectively. The essential oil increased the biofilm of Candida albicans by 38.25%, however, decreased the biofilm of Streptococcus mutans by 47.89% when treated with 500 µg/mL. Thus, the essential oil has a promising application in dentistry via inhibition of the growth of Candida albicans and Streptococcus mutans. However, the antibiofilm activity of the essential oil is only applicable for cariogenic Streptococcus mutans. © 2023 Informa UK Limited, trading as Taylor & Francis Group.
publisher Taylor and Francis Ltd.
issn 14786419
language English
format Article
accesstype All Open Access; Green Open Access
record_format scopus
collection Scopus
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