Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia

Introduction: There are insufficient data available regarding the outcome of cardiac arrest (CA) resuscitated in the emergency department in Malaysia. This study aims to determine the incidence of CA, the return of spontaneous circulation (ROSC), survival to admission (STA), survival to discharge (S...

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Published in:Medical Journal of Malaysia
Main Author: Mohamad M.I.K.; Mokhtar M.A.M.; Bin Isa M.R.; Mokhtar M.F.
Format: Article
Language:English
Published: Malaysian Medical Association 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173966780&partnerID=40&md5=de3d028bfa812da06a907523529eb9a6
id 2-s2.0-85173966780
spelling 2-s2.0-85173966780
Mohamad M.I.K.; Mokhtar M.A.M.; Bin Isa M.R.; Mokhtar M.F.
Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia
2023
Medical Journal of Malaysia
78
5

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173966780&partnerID=40&md5=de3d028bfa812da06a907523529eb9a6
Introduction: There are insufficient data available regarding the outcome of cardiac arrest (CA) resuscitated in the emergency department in Malaysia. This study aims to determine the incidence of CA, the return of spontaneous circulation (ROSC), survival to admission (STA), survival to discharge (STD) and factors influencing the overall outcome of CA. Material and Methods: This is a retrospective observational study done in Hospital Sg Buloh (HSB), a tertiary referral centre in an urban area located north of Kuala Lumpur, Malaysia's capital city, from January until December 2018, involving 289 patients. All cases with CPR and a sustained return of spontaneous circulation (ROSC) were included in the study and followed up until discharged or died in the hospital. Results: Out of 236 patients recruited, 25.8% achieved ROSC, 15.7% survived on admission, and 4.2% of patients were discharged alive. Of 74.1% of witnessed OHCA, only 17.5% received bystander CPR. Factors with favourable outcomes include CA in ED (p<0.001), the initial rhythm of ventricular fibrillation (p=0.003), defibrillation (p=0.024), OHCA witnessed by emergency medical services (EMS) (p=0.024) and intravenous adrenaline administration (p=0.001). When using multivariate regression analysis, positive outcomes were associated with the cardiac and respiratory cause of CA (Adjusted Odd Ratio (AOR) 3.66; 95% Confidence Intervals, 95%CI: 2.52-12.61 and AOR 8.76; 95%CI: 5.76-15.46, respectively) as well as OHCA witnessed by EMS (AOR 10.81; 95%CI: 1.84-19.52). Conclusions: Despite being an upper-middle-income country and having advancements in the healthcare system, a relatively lower STD rate among survivors of CA in the ED was observed in this study. There was underutilization of the EMS among patients with CA. The bystander CPR rate among patients with CA in Malaysia is also worryingly low. Aggressive community participation in cardiac arrest awareness programmes is much required. Additionally, in achieving better outcomes, implementing standardized post-resuscitation care protocols with existing resources will be a challenge for physicians managing cardiac arrest cases. © 2023, Malaysian Medical Association. All rights reserved.
Malaysian Medical Association
3005283
English
Article

author Mohamad M.I.K.; Mokhtar M.A.M.; Bin Isa M.R.; Mokhtar M.F.
spellingShingle Mohamad M.I.K.; Mokhtar M.A.M.; Bin Isa M.R.; Mokhtar M.F.
Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia
author_facet Mohamad M.I.K.; Mokhtar M.A.M.; Bin Isa M.R.; Mokhtar M.F.
author_sort Mohamad M.I.K.; Mokhtar M.A.M.; Bin Isa M.R.; Mokhtar M.F.
title Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia
title_short Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia
title_full Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia
title_fullStr Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia
title_full_unstemmed Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia
title_sort Outcomes of cardiopulmonary resuscitation in the emergency department of a tertiary hospital in Malaysia
publishDate 2023
container_title Medical Journal of Malaysia
container_volume 78
container_issue 5
doi_str_mv
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173966780&partnerID=40&md5=de3d028bfa812da06a907523529eb9a6
description Introduction: There are insufficient data available regarding the outcome of cardiac arrest (CA) resuscitated in the emergency department in Malaysia. This study aims to determine the incidence of CA, the return of spontaneous circulation (ROSC), survival to admission (STA), survival to discharge (STD) and factors influencing the overall outcome of CA. Material and Methods: This is a retrospective observational study done in Hospital Sg Buloh (HSB), a tertiary referral centre in an urban area located north of Kuala Lumpur, Malaysia's capital city, from January until December 2018, involving 289 patients. All cases with CPR and a sustained return of spontaneous circulation (ROSC) were included in the study and followed up until discharged or died in the hospital. Results: Out of 236 patients recruited, 25.8% achieved ROSC, 15.7% survived on admission, and 4.2% of patients were discharged alive. Of 74.1% of witnessed OHCA, only 17.5% received bystander CPR. Factors with favourable outcomes include CA in ED (p<0.001), the initial rhythm of ventricular fibrillation (p=0.003), defibrillation (p=0.024), OHCA witnessed by emergency medical services (EMS) (p=0.024) and intravenous adrenaline administration (p=0.001). When using multivariate regression analysis, positive outcomes were associated with the cardiac and respiratory cause of CA (Adjusted Odd Ratio (AOR) 3.66; 95% Confidence Intervals, 95%CI: 2.52-12.61 and AOR 8.76; 95%CI: 5.76-15.46, respectively) as well as OHCA witnessed by EMS (AOR 10.81; 95%CI: 1.84-19.52). Conclusions: Despite being an upper-middle-income country and having advancements in the healthcare system, a relatively lower STD rate among survivors of CA in the ED was observed in this study. There was underutilization of the EMS among patients with CA. The bystander CPR rate among patients with CA in Malaysia is also worryingly low. Aggressive community participation in cardiac arrest awareness programmes is much required. Additionally, in achieving better outcomes, implementing standardized post-resuscitation care protocols with existing resources will be a challenge for physicians managing cardiac arrest cases. © 2023, Malaysian Medical Association. All rights reserved.
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