The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches

The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches

The analysis of drugs and toxicants in postmortem samples is a challenging task due to the complexity of the sample matrix and the low concentrations of the analytes. Over the last three decades, green sample preparation techniques such as sorbent-based and solvent-based microextraction methods have...

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Published in:TrAC - Trends in Analytical Chemistry
Main Author: Jain R.; Yahaya N.; Mohamed A.H.; Kabir A.; Chandrawanshi L.P.; AbdElrahman M.; Ghoneim M.M.; Bakkannavar S.M.
Format: Review
Language:English
Published: Elsevier B.V. 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173619271&doi=10.1016%2fj.trac.2023.117354&partnerID=40&md5=db2f7f5a794e04211c9d13167d35c389
id 2-s2.0-85173619271
spelling 2-s2.0-85173619271
Jain R.; Yahaya N.; Mohamed A.H.; Kabir A.; Chandrawanshi L.P.; AbdElrahman M.; Ghoneim M.M.; Bakkannavar S.M.
The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches
2023
TrAC - Trends in Analytical Chemistry
168

10.1016/j.trac.2023.117354
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173619271&doi=10.1016%2fj.trac.2023.117354&partnerID=40&md5=db2f7f5a794e04211c9d13167d35c389
The analysis of drugs and toxicants in postmortem samples is a challenging task due to the complexity of the sample matrix and the low concentrations of the analytes. Over the last three decades, green sample preparation techniques such as sorbent-based and solvent-based microextraction methods have gained popularity as efficient and eco-friendly alternatives to traditional sample preparation methods. In this review article, we discuss various green sample preparation approaches that have been used for the analysis of drugs and toxicants in postmortem samples. The review article also highlights the potential future direction of green sample preparation techniques in postmortem toxicology. Finally, as an example, whiteness for selected analytical methods for determining antidepressants in postmortem samples has been evaluated by recently introduced RGB 12 algorithm. The information presented in this review is intended to serve as a valuable resource for researchers and practitioners in the field of postmortem toxicology. © 2023 Elsevier B.V.
Elsevier B.V.
1659936
English
Review
author Jain R.; Yahaya N.; Mohamed A.H.; Kabir A.; Chandrawanshi L.P.; AbdElrahman M.; Ghoneim M.M.; Bakkannavar S.M.
spellingShingle Jain R.; Yahaya N.; Mohamed A.H.; Kabir A.; Chandrawanshi L.P.; AbdElrahman M.; Ghoneim M.M.; Bakkannavar S.M.
The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches
author_facet Jain R.; Yahaya N.; Mohamed A.H.; Kabir A.; Chandrawanshi L.P.; AbdElrahman M.; Ghoneim M.M.; Bakkannavar S.M.
author_sort Jain R.; Yahaya N.; Mohamed A.H.; Kabir A.; Chandrawanshi L.P.; AbdElrahman M.; Ghoneim M.M.; Bakkannavar S.M.
title The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches
title_short The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches
title_full The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches
title_fullStr The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches
title_full_unstemmed The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches
title_sort The role of emerging sample preparation methods in postmortem toxicology: Green and sustainable approaches
publishDate 2023
container_title TrAC - Trends in Analytical Chemistry
container_volume 168
container_issue
doi_str_mv 10.1016/j.trac.2023.117354
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85173619271&doi=10.1016%2fj.trac.2023.117354&partnerID=40&md5=db2f7f5a794e04211c9d13167d35c389
description The analysis of drugs and toxicants in postmortem samples is a challenging task due to the complexity of the sample matrix and the low concentrations of the analytes. Over the last three decades, green sample preparation techniques such as sorbent-based and solvent-based microextraction methods have gained popularity as efficient and eco-friendly alternatives to traditional sample preparation methods. In this review article, we discuss various green sample preparation approaches that have been used for the analysis of drugs and toxicants in postmortem samples. The review article also highlights the potential future direction of green sample preparation techniques in postmortem toxicology. Finally, as an example, whiteness for selected analytical methods for determining antidepressants in postmortem samples has been evaluated by recently introduced RGB 12 algorithm. The information presented in this review is intended to serve as a valuable resource for researchers and practitioners in the field of postmortem toxicology. © 2023 Elsevier B.V.
publisher Elsevier B.V.
issn 1659936
language English
format Review
accesstype
record_format scopus
collection Scopus
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