Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine

Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine

This comprehensive review article discusses the biomedical applications of carbon nanotubes (CNTs) with unique inherent chemical and physical attributes. The findings of different researchers in the field of CNT, their functionalization, and their biomedical applications are focused on. In-vitro and...

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Published in:Inorganic Chemistry Communications
Main Author: Ijaz H.; Mahmood A.; Abdel-Daim M.M.; Sarfraz R.M.; Zaman M.; Zafar N.; Alshehery S.; Salem-Bekhit M.M.; Ali M.A.; Eltayeb L.B.; Benguerba Y.
Format: Review
Language:English
Published: Elsevier B.V. 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165265881&doi=10.1016%2fj.inoche.2023.111020&partnerID=40&md5=2c9eebec5321ac9ec2a0b280748aea6f
id 2-s2.0-85165265881
spelling 2-s2.0-85165265881
Ijaz H.; Mahmood A.; Abdel-Daim M.M.; Sarfraz R.M.; Zaman M.; Zafar N.; Alshehery S.; Salem-Bekhit M.M.; Ali M.A.; Eltayeb L.B.; Benguerba Y.
Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine
2023
Inorganic Chemistry Communications
155

10.1016/j.inoche.2023.111020
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165265881&doi=10.1016%2fj.inoche.2023.111020&partnerID=40&md5=2c9eebec5321ac9ec2a0b280748aea6f
This comprehensive review article discusses the biomedical applications of carbon nanotubes (CNTs) with unique inherent chemical and physical attributes. The findings of different researchers in the field of CNT, their functionalization, and their biomedical applications are focused on. In-vitro and in-vivo drug delivery have been investigated, mainly using doxorubicin for anti-cancer treatment. Additionally, due to their Raman and photoluminescence properties, single-wall carbon nanotubes (SWCNTs) have shown promise as optical contrast agents for cell imaging. In vitro and in vivo toxicity studies have demonstrated the biocompatibility and safety of hydrophilic serum-stable CNTs. The biodistribution of CNTs is influenced by functionalization, with small particles accumulating in the reticuloendothelial system (RES) of vital organs such as the heart, kidney, and spleen. The significant potential of CNTs in various biomedical applications is highlighted in this review. © 2023
Elsevier B.V.
13877003
English
Review
author Ijaz H.; Mahmood A.; Abdel-Daim M.M.; Sarfraz R.M.; Zaman M.; Zafar N.; Alshehery S.; Salem-Bekhit M.M.; Ali M.A.; Eltayeb L.B.; Benguerba Y.
spellingShingle Ijaz H.; Mahmood A.; Abdel-Daim M.M.; Sarfraz R.M.; Zaman M.; Zafar N.; Alshehery S.; Salem-Bekhit M.M.; Ali M.A.; Eltayeb L.B.; Benguerba Y.
Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine
author_facet Ijaz H.; Mahmood A.; Abdel-Daim M.M.; Sarfraz R.M.; Zaman M.; Zafar N.; Alshehery S.; Salem-Bekhit M.M.; Ali M.A.; Eltayeb L.B.; Benguerba Y.
author_sort Ijaz H.; Mahmood A.; Abdel-Daim M.M.; Sarfraz R.M.; Zaman M.; Zafar N.; Alshehery S.; Salem-Bekhit M.M.; Ali M.A.; Eltayeb L.B.; Benguerba Y.
title Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine
title_short Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine
title_full Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine
title_fullStr Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine
title_full_unstemmed Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine
title_sort Review on carbon nanotubes (CNTs) and their chemical and physical characteristics, with particular emphasis on potential applications in biomedicine
publishDate 2023
container_title Inorganic Chemistry Communications
container_volume 155
container_issue
doi_str_mv 10.1016/j.inoche.2023.111020
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165265881&doi=10.1016%2fj.inoche.2023.111020&partnerID=40&md5=2c9eebec5321ac9ec2a0b280748aea6f
description This comprehensive review article discusses the biomedical applications of carbon nanotubes (CNTs) with unique inherent chemical and physical attributes. The findings of different researchers in the field of CNT, their functionalization, and their biomedical applications are focused on. In-vitro and in-vivo drug delivery have been investigated, mainly using doxorubicin for anti-cancer treatment. Additionally, due to their Raman and photoluminescence properties, single-wall carbon nanotubes (SWCNTs) have shown promise as optical contrast agents for cell imaging. In vitro and in vivo toxicity studies have demonstrated the biocompatibility and safety of hydrophilic serum-stable CNTs. The biodistribution of CNTs is influenced by functionalization, with small particles accumulating in the reticuloendothelial system (RES) of vital organs such as the heart, kidney, and spleen. The significant potential of CNTs in various biomedical applications is highlighted in this review. © 2023
publisher Elsevier B.V.
issn 13877003
language English
format Review
accesstype
record_format scopus
collection Scopus
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