Synthesis, in vitro biological analysis and molecular docking studies of new thiadiazole-based thiourea derivatives as dual inhibitors of a-amylase and a-glucosidase

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Synthesis, in vitro biological analysis and molecular docking studies of new thiadiazole-based thiourea derivatives as dual inhibitors of a-amylase and a-glucosidase

Diabetes mellitus is a syndrome that is caused due to the imbalance of insulin production in the body. In the present study we have synthesized a class of fifteen compounds (1–15) based on thiadiazole-bearing thiourea that were assessed for in vitro alpha-amylase and alpha-glucosidase inhibitory pot...

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Bibliographic Details
Published in:	Arabian Journal of Chemistry
Main Author:	Khan I.; Rehman W.; Rahim F.; Hussain R.; Khan S.; Rasheed L.; Alanazi A.S.; Hefnawy M.; Alanazi M.M.; Shah S.A.A.; Taha M.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2023
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85162946909&doi=10.1016%2fj.arabjc.2023.105078&partnerID=40&md5=fb343f6576bc4267182208147dd6ad1a

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