Convergent synthesis, kinetics insight and allosteric computational ascriptions of thiazole-(5-aryl)oxadiazole hybrids embraced with propanamides as alkaline phosphatase inhibitors

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Convergent synthesis, kinetics insight and allosteric computational ascriptions of thiazole-(5-aryl)oxadiazole hybrids embraced with propanamides as alkaline phosphatase inhibitors

Considering the varied pharmacological prominence of thiazole and oxadiazole heterocyclic moieties, a unique series of bi-heterocyclic hybrids, 8a-h, was synthesized in a convergent manner. The structures of newly synthesized compounds were characterized by 1H-NMR, 13C-NMR, and IR spectral studies....

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Bibliographic Details
Published in:	RSC Advances
Main Author:	Butt A.R.S.; Abbasi M.A.; Aziz-Ur-Rehman N.; Siddiqui S.Z.; Muhammad S.; Raza H.; Shah S.A.A.; Shahid M.; Alsehemi A.G.; Kim S.J.
Format:	Article
Language:	English
Published:	Royal Society of Chemistry 2023
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85159781993&doi=10.1039%2fd3ra01348k&partnerID=40&md5=00482b22e99410fbbeb527041ed9636b

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