Synthesis, in vitro thymidine phosphorylase inhibitory activity and molecular docking study of novel pyridine-derived bis-oxadiazole bearing bis-schiff base derivatives
The current study has afforded twelve analogs (4a-l) of pyridine-derived bis-oxadiazole containing bis-schiff base and subsequently evaluated for their potential to inhibit thymidine phosphorylase(in vitro). All the synthesized analogs were structurally elucidated using various spectroscopic tools i...
Published in: | Arabian Journal of Chemistry |
---|---|
Main Author: | Hussain R.; Rehman W.; Rahim F.; Khan S.; Alanazi A.S.; Alanazi M.M.; Rasheed L.; Khan Y.; Adnan. Ali. Shah S.; Taha M. |
Format: | Article |
Language: | English |
Published: |
Elsevier B.V.
2023
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150866913&doi=10.1016%2fj.arabjc.2023.104773&partnerID=40&md5=0a56b031c509a84375b1de776fbeffc9 |
Similar Items
-
Synthesis, molecular docking study and in vitro thymidine phosphorylase inhibitory potential of oxadiazole derivatives
by: Ullah H.; Rahim F.; Taha M.; Uddin I.; Wadood A.; Shah S.A.A.; Farooq R.K.; Nawaz M.; Wahab Z.; Khan K.M.
Published: (2018) -
Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase
by: Taha M.; Rashid U.; Imran S.; Ali M.
Published: (2018) -
Synthesis, in vitro alpha-glucosidase inhibitory potential of benzimidazole bearing bis-Schiff bases and their molecular docking study
by: Rahim F.; Zaman K.; Taha M.; Ullah H.; Ghufran M.; Wadood A.; Rehman W.; Uddin N.; Shah S.A.A.; Sajid M.; Nawaz F.; Khan K.M.
Published: (2020) -
Synthesis, molecular docking study and thymidine phosphorylase inhibitory activity of 3-formylcoumarin derivatives
by: Taha M.; Adnan Ali Shah S.; Afifi M.; Imran S.; Sultan S.; Rahim F.; Hadiani Ismail N.; Mohammed Khan K.
Published: (2018) -
Experimental and computational profiling of novel bis-Schiff base derivatives bearing α-naphthalene moiety as potential tyrosinase inhibitors
by: Shah T.A.; Alam A.; Zainab; Khan M.; Elhenawy A.A.; Ayaz M.; Ali M.; Latif A.; Shah S.A.A.; Ahmad M.
Published: (2025)