In Silico Analysis of 14-Deoxy 11, 12-Didehydro Andrographolide (AGP 2) From Sambiloto (Andrographis paniculata) As Drug Candidate Against SARS-CoV-2

QR Code

In Silico Analysis of 14-Deoxy 11, 12-Didehydro Andrographolide (AGP 2) From Sambiloto (Andrographis paniculata) As Drug Candidate Against SARS-CoV-2

The outbreak of the COVID-19 pandemic in the world has urged researchers to develop a vaccine or therapeutic drugs to fight this virus. This study aimed to assay 14 deoxy-11,12-didehydroandrographolide (AGP 2) ability as an inhibitor of 3-chymotrypsin like-protease (3CLPro), Papain-like protease (PL...

Full description

Bibliographic Details
Published in:	HAYATI Journal of Biosciences
Main Author:	Astria M.V.; Waluyo L.; Latifa R.; Nuryady M.M.; Susetyarini R.E.; Bin Labo M.A.
Format:	Article
Language:	English
Published:	Bogor Agricultural University 2023
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150155977&doi=10.4308%2fhjb.30.3.480-490&partnerID=40&md5=0fd1e776d7ed0f27c9cd6e75808f5420

Similar Items

ANTIBACTERIAL ACTIVITY OF Andrographis paniculata AQUEOUS EXTRACT AGAINST ORAL PATHOGENS
by: Muhamad Alojid A.A.; Tuan Kub T.N.; Miran H.; Mohamad S.; Ismail T.N.N.T.; Manah T.; Abdullah R.; Hassan S.A.; Hassan S.A.; Salmuna Z.N.; Ahmad N.N.
Published: (2021)

Antifungal properties of Andrographis paniculata extracts as potential biofungicides: a review
by: Kalit S.N.D.M.; Zain W.Z.W.M.; Ghazali A.H.; Ramli N.W.; Aziman N.; Hamzah F.; Hamid N.A.; Musa S.A.N.C.
Published: (2024)

The antifungal activity of Andrographis paniculata and its effects on Oryza sativa germination and growth
by: Ghazali A.H.; Zain W.Z.W.M.; Kalit S.N.D.M.; Wahab M.Z.A.; Ramli N.W.; Hamid N.A.; Musa S.A.N.C.; Aziman N.
Published: (2024)

Targeting signaling pathways with andrographolide in cancer therapy (Review)
by: Shaharudin N.S.; Singh G.K.S.; Kek T.L.; Sultan S.
Published: (2024)

2-Furoic piperazide derivatives as promising drug candidates of type 2 diabetes and Alzheimer's diseases: In vitro and in silico studies
by: Abbasi M.A.; Hassan M.; ur-Rehman A.; Siddiqui S.Z.; Hussain G.; Shah S.A.A.; Ashraf M.; Shahid M.; Seo S.Y.
Published: (2018)

Anti-malarial and cytokine-modulating effects of andrographolide in a murine model of malarial infection
by: Hassan W.R.M.; Basir R.; Ali A.H.; Embi N.; Sidek H.M.
Published: (2019)

Unravelling The Bioactivities of Acmella paniculata Extract-Mediated Green Deep Eutectic Solvent of Citric Acid Monohydrate and Glycerol
by: Sivaraj R.S.; Hanaphi R.M.; Yusof R.
Published: (2024)

Dual actions of gallic acid and andrographolide trigger AdipoR1 to stimulate insulin secretion in a streptozotocin-induced diabetes rat model
by: Wong T.S.; Mohamed Tap F.; Hashim Z.; Abdul Majid F.A.; Zakaria N.H.; Siahaan P.; Mogadem A.
Published: (2023)

Facile method to synthesize of magnesium-graphene nano sheets for candidate of primary battery electrode
by: Siburian R.; Paiman S.; Hutagalung F.; Ali A.M.M.; Simatupang L.; Goei R.; Rusop M.M.
Published: (2022)

Application of Reverse Vaccinology and Immunoinformatic Strategies for the Identification of Vaccine Candidates Against Shigella flexneri
by: Leow C.Y.; Chuah C.; Abdul Majeed A.B.; Mohd Nor N.
Published: (2022)

Mass spectrometry-based immunopeptidomics and computational vaccinology strategies for the identification of universal Shigella immunogenic candidates
by: Mohammad Shabani N.R.; Khairul Hisyam Ismail C.M.; Anthony A.A.; Leow C.H.; Chuah C.; Abdul Majeed A.B.; Nor N.M.; He Y.; Banga Singh K.K.; Leow C.Y.
Published: (2022)

Synthesis, biological evaluation and molecular docking study of benzimidazole derivatives as α-glucosidase inhibitors and anti-diabetes candidates
by: Hayat S.; Ullah H.; Rahim F.; Ullah I.; Taha M.; Iqbal N.; Khan F.; Khan M.S.; Shah S.A.A.; Wadood A.; Sajid M.; Abdalla A.N.
Published: (2023)

Synthesis of New Triazole-Based Thiosemicarbazone Derivatives as Anti-Alzheimer’s Disease Candidates: Evidence-Based In Vitro Study
by: Rahim F.; Ullah H.; Taha M.; Hussain R.; Sarfraz M.; Iqbal R.; Iqbal N.; Khan S.; Ali Shah S.A.; Albalawi M.A.; Abdelaziz M.A.; Alatawi F.S.; Alasmari A.; Sakran M.I.; Zidan N.; Jafri I.; Khan K.M.
Published: (2023)

Factors Influencing the Selection of Dentistry as a Career Among Prospective Candidates: A Multicentre Cross-Sectional Study
by: Abdul Hamid N.; Jaafar A.; Asming N.; Suria N.; Ho T.; Lim Z.; Lim T.
Published: (2024)

Factors Influencing the Selection of Dentistry as a Career Among Prospective Candidates: A Multicentre Cross-Sectional Study
by: Hamid, et al.
Published: (2024)

Genome-wide analysis of copy number variation identifies candidate gene loci associated with the progression of non-alcoholic fatty liver disease
by: Zain S.M.; Mohamed R.; Cooper D.N.; Razali R.; Rampal S.; Mahadeva S.; Chan W.-K.; Anwar A.; Rosli N.S.M.; Mahfudz A.S.; Cheah P.-L.; Basu R.C.; Mohamed Z.
Published: (2014)

Anti-candidal Activity of Crude Extracts and Compounds from Dipterocarpus verrucosus Foxw. Ex Sloot, Dipterocarpus cornutus Dyer and Dipterocarpus crinitus Dyer
by: Mohd Zain W.Z.W.; Yusoff N.A.H.; Rukayadi Y.; Aziman N.; Windayani N.
Published: (2024)

Vibrio harveyi protease deletion mutant as a live attenuated vaccine candidate against vibriosis and transcriptome profiling following vaccination for Epinephelus fuscoguttatus
by: Mohd-Aris A.; Saad M.-Z.; Daud H.M.; Yusof M.T.; Ina-Salwany M.Y.
Published: (2019)

18 F-labeled Bisphosphonate as an Alternative Candidate to the Gold Standard[18F]sodium fluoride ([18F]NaF) for PET Bone Imaging
by: Hassan H.; Othman M.F.; Razak H.R.A.
Published: (2021)

Revisiting the Reaction of Ru3(CO)12 with Ph2PCH2CH2PPh2: Synthesis, Crystal Structure, and DFT Study of Ru3(CO)8(µPh2PCH2CH2PPh2)2
by: Azharan H.I.M.N.; Hamali M.A.; Tajuddin A.M.; Sapari S.; Razak F.I.A.; Pungot N.H.; Ahmad S.N.; Sirat S.S.
Published: (2024)

Crystal structure of 2,2'-(((2,2-dimethylpropane-1,3-diyl)bis(azanylylidene))- bis(methanylylidene))bis(4-methoxyphenol)palladium(II)
by: Ahmad S.N.; Bahron H.; Tajuddin A.M.; Sukeri M.M.Y.
Published: (2017)

Synthesis and optical properties of novel Bi2O3–Li2O–Al2O3–TeO2 glasses
by: Zarzali Shah A.; Zaid M.H.M.; Matori K.A.; Hisam R.
Published: (2024)

[3-Methoxy-5-(methoxycarbonyl)isoxazol-4-yl](4-methoxyphenyl)iodonium 2,2,2-trifluoroacetate
by: Manan M.A.F.A.; Cordes D.B.; Slawin A.M.Z.; O’Hagan D.
Published: (2023)

2-(2′-Pyridyl) benzimidazole derivatives and their urease inhibitory activity
by: Saify Z.S.; Kamil A.; Akhtar S.; Taha M.; Khan A.; Khan K.M.; Jahan S.; Rahim F.; Perveen S.; Choudhary M.I.
Published: (2014)

Design, synthesis and biological evaluation of 3-(2-aminooxazol-5-yl)-2H-chromen-2-one derivatives
by: Kakkar S.; Kumar S.; Lim S.M.; Ramasamy K.; Mani V.; Shah S.A.A.; Narasimhan B.
Published: (2018)

Synthesis and characterisation of layered double hydroxides with varying divalent metal cations: Mg2+, Zn2+, Ca2+
by: Limau Jadam M.; Halimah Sarijo S.; Jubri Z.
Published: (2022)

The intergenerational effects of oligomeric proanthocyanidins on expression of Sult2a2, Sult2al1 and Sult2a1 in Bisphenol A-exposed male rats
by: Siti-Aishah Z.; Razif D.; Mohd Hafizi M.; Fatin N.O.; Nur Hilwani I.; Fatin Nadzirah Z.; Nina Keterina H.; Mastura A.M.
Published: (2020)

5,8-Dihydroxy-2,2-dimethyl-12-(3-methylbut-2-enyl)pyrano[3,2-b]xanthen-6-one (brasixanthone B)
by: Binti Seruji N.M.U.; Rosli M.M.; Jong V.Y.M.; Karunakaran T.; Lizazman M.A.; Marlina A.; Binti Halid Y.Y.
Published: (2023)

Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians
by: Muthiah Y.D.; Lee W.L.; Teh L.K.; Ong C.E.; Ismail R.
Published: (2005)

2-(2'-pyridyl) benzimidazole analogs and their ß-glucuronidase inhibitory activity
by: Kamil A.; Akhtar S.; Noureen S.; Saify Z.S.; Jahan S.; Khan K.M.; Rahim F.; Taha M.; Mushtaq N.; Arif M.; Perveen S.; Chaudhary M.I.
Published: (2015)

(E)-2-Methoxy-N'-(2,4,6-trihydroxybenzylidene)benzohydrazide
by: Taha M.; Baharudin M.S.; Ismail N.H.; Shah S.A.A.; Yousuf S.
Published: (2013)

TIO2-MOS2 PAPER BASED MEMBRANE FOR SOLAR EVAPORATION
by: Fuzil N.S.; Othman N.H.; Mat-Shayuti M.S.; Alias N.H.; Marpani F.; Shahruddin M.Z.; Rahman N.A.; Rashid Z.A.; Razlan M.R.M.; Lau W.J.; Othman M.H.D.; Ismail A.F.; Kusworo T.D.; Ul-Hamid A.
Published: (2024)

Effects of mixed TeO2-B2O3glass formers on optical and radiation shielding properties of 70[ xTeO2+(1- x)B2O3]+15Na2O + 15K2O glass system
by: Shuhaimi S.A.; Sayyed M.I.; Hila F.C.; Anis A.L.; Iskandar S.M.; Zaid M.H.M.; Azlan M.N.; Nazrin S.N.; Yusof N.N.; Hisam R.
Published: (2022)

Phase development in La2O3 doped Al2O3:TiO2 ceramic membranes
by: Stefan Björkert U.; Mayappan R.; Holland D.; Lewis M.H.
Published: (1999)

Enhanced superconducting transition temperature for Cr-substituted Tl2Ba2CaCu2O8-δ
by: Humaidi S.; Jannah A.N.; Alias A.; Abd-Shukor R.
Published: (2023)

Role of Gd2O3 on structure rearrangement and elastic properties ZnO-Al2O3-B2O3-SiO2 glass system
by: Ismail N.A.N.; Zaid M.H.M.; Matori K.A.; Fen Y.W.; Cheong W.M.; Loh Z.W.; Shah A.Z.; Hisam R.; Azlan M.N.; Iskandar S.M.
Published: (2023)

Comprehensive study on structural, elastic and radiation shielding abilities of novel quaternary Bi 2 O 3-TeO 2-Li 2 O-Al 2 O 3 glasses
by: Shah, et al.
Published: (2024)

Comprehensive study on structural, elastic and radiation shielding abilities of novel quaternary Bi2O3–TeO2–Li2O–Al2O3 glasses
by: Shah A.Z.; Mohd Zaid M.H.; Matori K.A.; Yaakob Y.; Sarmani A.R.; Hisam R.
Published: (2024)

Effect of Cr2O3 loading on the properties and cracking activity of Pt/Cr2O3-ZrO2
by: Annuar N.H.R.; Triwahyono S.; Jalil A.A.; Basar N.; Abdullah T.A.T.; Ahmad A.
Published: (2017)

Synthesis, characterization, monoamine oxidase inhibition, molecular docking and dynamic simulations of novel 2,1-benzothiazine-2,2-dioxide derivatives
by: Ahmad S.; Zaib S.; Jalil S.; Shafiq M.; Ahmad M.; Sultan S.; Iqbal M.; Aslam S.; Iqbal J.
Published: (2018)