Essential oils composition of Litsea glauca and Litsea fulva and their anticholinesterase inhibitory activity

This study was designed to examine the essential oils compositions of Litsea glauca Siebold and Litsea fulva Fern.-Vill. growing in Malaysia. The essential oils were achieved by hydrodistillation and fully characterized by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS)....

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Bibliographic Details
Published in:Natural Product Research
Main Author: Salleh W.M.N.H.W.; Salihu A.S.; Ab Ghani N.
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85148239675&doi=10.1080%2f14786419.2023.2180507&partnerID=40&md5=2d2880c9971dc1f5b560001fccdbe7c2
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Summary:This study was designed to examine the essential oils compositions of Litsea glauca Siebold and Litsea fulva Fern.-Vill. growing in Malaysia. The essential oils were achieved by hydrodistillation and fully characterized by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The study identified 17 and 19 components from the leaf oils from L. glauca (80.7%) and L. fulva (81.5%), respectively. The major components of L. glauca oil were β-selinene (30.8%), β-calacorene (11.3%), tridecanal (7.6%), isophytol (4.8%) and β-eudesmol (4.5%); whereas in L. fulva oil gave β-caryophyllene (27.8%), caryophyllene oxide (12.8%), α-cadinol (6.3%), (E)-nerolidol (5.7%), β-selinene (5.5%) and tridecanal (5.0%). Anticholinesterase activity was evaluated using Ellman method. The essential oils showed moderate inhibitory activity on acetylcholinesterase and butyrylcholinesterase assays. Our findings demonstrate that the essential oil could be very useful for the characterization, pharmaceutical, and therapeutic applications of the essential oil from the genus Litsea. © 2023 Informa UK Limited, trading as Taylor & Francis Group.
ISSN:14786419
DOI:10.1080/14786419.2023.2180507