Chemical Components and Anticholinesterase Activity of Piper ornatum N.E.Br Volatile Oil

• Published in: Malaysian Journal of Chemistry
• Main Authors: Nik Mohammed Ainul Azman N.N.A., Wan Salleh W.M.N.H., Ab Ghani N.
• Format: Article
• Language: English
• Published: Malaysian Institute of Chemistry 2022
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147182645&partnerID=40&md5=eb81407aac7ef60e039338b52db0fe7b

This study reports volatile oil components and anticholinesterase inhibitory activity of Piper ornatum N.E.Br (Piperaceae) essential oil collected from Malaysia. The essential oil was obtained by hydrodistillation and fully analysed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Twenty-seven chemical components were identified representing 79.6% of the total oil. The essential oil contains caryophyllene oxide (31.5%), spathulenol (5.9%), aromadendrene (4.9%), and β-caryophyllene epoxide (4.5%). Anticholinesterase activity was evaluated using Ellman method. The essential oil showed significant inhibitory activity against acetylcholinesterase (I%: 70.2%) and butyrylcholinesterase (I%: 75.8%) assays. © 2022 Malaysian Institute of Chemistry. All rights reserved.