Synthesis, DFT Studies, Molecular Docking and Biological Activity Evaluation of Thiazole-Sulfonamide Derivatives as Potent Alzheimer’s Inhibitors
Alzheimer’s disease is a major public brain condition that has resulted in many deaths, as revealed by the World Health Organization (WHO). Conventional Alzheimer’s treatments such as chemotherapy, surgery, and radiotherapy are not very effective and are usually associated with several adverse effec...
Published in: | Molecules |
---|---|
Main Author: | Khan S.; Ullah H.; Taha M.; Rahim F.; Sarfraz M.; Iqbal R.; Iqbal N.; Hussain R.; Ali Shah S.A.; Ayub K.; Albalawi M.A.; Abdelaziz M.A.; Alatawi F.S.; Khan K.M. |
Format: | Article |
Language: | English |
Published: |
MDPI
2023
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146720100&doi=10.3390%2fmolecules28020559&partnerID=40&md5=71c3f6a6b523316faa786f7fc6601e45 |
Similar Items
-
Multipotent Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease: Synthesis, Biological Analysis and Molecular Docking Study of Benzimidazole-Based Thiazole Derivatives
by: Hussain R.; Ullah H.; Rahim F.; Sarfraz M.; Taha M.; Iqbal R.; Rehman W.; Khan S.; Shah S.A.A.; Hyder S.; Alhomrani M.; Alamri A.S.; Abdulaziz O.; Abdelaziz M.A.
Published: (2022) -
Synthesis of New Triazole-Based Thiosemicarbazone Derivatives as Anti-Alzheimer’s Disease Candidates: Evidence-Based In Vitro Study
by: Rahim F.; Ullah H.; Taha M.; Hussain R.; Sarfraz M.; Iqbal R.; Iqbal N.; Khan S.; Ali Shah S.A.; Albalawi M.A.; Abdelaziz M.A.; Alatawi F.S.; Alasmari A.; Sakran M.I.; Zidan N.; Jafri I.; Khan K.M.
Published: (2023) -
Benzimidazole Bearing Thiosemicarbazone Derivatives Act as Potent α-Amylase and α-Glucosidase Inhibitors; Synthesis, Bioactivity Screening and Molecular Docking Study
by: Ullah H.; Khan S.; Rahim F.; Taha M.; Iqbal R.; Sarfraz M.; Shah S.A.A.; Sajid M.; Awad M.F.; Omran A.; Albalawi M.A.; Abdelaziz M.A.; Al Areefy A.; Jafri I.
Published: (2022) -
Synthesis, biological evaluation and molecular docking study of oxindole based chalcone analogues as potent anti-Alzheimer agents
by: Taha M.; Sadia H.; Rahim F.; Khan M.I.; Hayat S.; Iqbal N.; Nawaz F.; Ullah H.; Zada H.; Shah S.A.A.; Wadood A.; Farooq R.K.; Khan K.M.
Published: (2023) -
Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease
by: Rahim F.; Javed M.T.; Ullah H.; Wadood A.; Taha M.; Ashraf M.; Qurat-Ul-Ain; Khan M.A.; Khan F.; Mirza S.; Khan K.M.
Published: (2015)