Stereospecific/stereoselective nickel catalyzed reductive cross-coupling: An efficient tool for the synthesis of biological active targeted molecules
Reductive cross-electrophile transformations have recently been made into a robust and long-lasting synthetic technique for the production of specific C[sbnd]C bonds. The use of inexpensive and plentiful electrophiles eliminates the need for pre-formation and handling of organometallics. In stereosp...
| Published in: | Journal of Saudi Chemical Society |
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| Main Author: | |
| Format: | Review |
| Language: | English |
| Published: |
Elsevier B.V.
2023
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146252728&doi=10.1016%2fj.jscs.2022.101589&partnerID=40&md5=dc1af534ec5dd2f5d2113c1bedef61a0 |
| Summary: | Reductive cross-electrophile transformations have recently been made into a robust and long-lasting synthetic technique for the production of specific C[sbnd]C bonds. The use of inexpensive and plentiful electrophiles eliminates the need for pre-formation and handling of organometallics. In stereospecific reductive cross-coupling, nickel is one of the most cost-effective and flexible transition metals. This paper examines current developments in nickel catalyzed reductive cross-coupling reactions and their potential application for the synthesis of biologically active molecules over the previous nine years. © 2022 |
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| ISSN: | 13196103 |
| DOI: | 10.1016/j.jscs.2022.101589 |