Discovering biological efficacy of new thiadiazole as effective inhibitors of urease, glycation, and (DPPH) scavengers: Biochemical and in silico study

Thiadiazole is a potential class of α-glucosidase, β-glucuronidase, and anti-leishmanial inhibitors. Our aim was to develop thiadiazole based dual inhibitors for urease glycation inhibition and (DDPH) scavenging activity. Pyridine-based-thiadiazole analogs (1–18) were synthesized and characterized t...

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Bibliographic Details
Published in:Journal of Molecular Structure
Main Author: Taha M.; Imran S.; Rahim F.; Uddin N.; Iqbal N.; Khan K.M.; Farooq R.K.; Alomari M.; Islam I.; Algheribe S.
Format: Article
Language:English
Published: Elsevier B.V. 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141287162&doi=10.1016%2fj.molstruc.2022.134449&partnerID=40&md5=31cc37b083234dc40107e9711af90b0d