Structure–Activity Relationship Analysis of Flavonoids and Its Inhibitory Activity Against BACE1 Enzyme Toward a Better Therapy for Alzheimer’s Disease
Drug development in Alzheimer’s disease (AD) suffers from a high attrition rate. In 2021, 117 agents tested in phases I and II and 36 agents tested in phase III were discontinued. Natural product compounds may be good lead compounds for AD as they contain functional groups that are important for bin...
| Published in: | Frontiers in Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133900050&doi=10.3389%2ffchem.2022.874615&partnerID=40&md5=998683f37535cb98794ab954929b27e1 |