Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in t...

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Bibliographic Details
Published in:Natural Product Sciences
Main Author: Tanjung M.; Tjahjandarie T.S.; Mardhiyyah S.; Rahman G.Z.; Aldin M.F.; Saputri R.D.; Ahmat N.
Format: Article
Language:English
Published: Korean Society of Pharmacognosy 2022
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133869299&doi=10.20307%2fnps.2022.28.2.58&partnerID=40&md5=2e8d72bf86c07319fbe2b9d49dd378cd
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Summary:Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 µM. © 2022, Korean Society of Pharmacognosy. All rights reserved.
ISSN:12263907
DOI:10.20307/nps.2022.28.2.58