Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes
A new asymmetric synthesis of several hydroxy N,O-heterobicyclic octanes is described in this paper. The synthesis employed Salen catalysed epoxide ring opening of the starting material meso-cyclohexene followed by the azide reduction and NBoc protection of (1S,6S)-6-azido-3-cyclohexenol, allylic hy...
| Published in: | Malaysian Journal of Chemistry |
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| Format: | Conference paper |
| Language: | English |
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Malaysian Institute of Chemistry
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133513339&partnerID=40&md5=a1bf76ed85bd8ee08de14a84a9df42c3 |
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2-s2.0-85133513339 Sharoman N.S.; Imran S.; Ali M.T.M. Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes 2022 Malaysian Journal of Chemistry 24 2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133513339&partnerID=40&md5=a1bf76ed85bd8ee08de14a84a9df42c3 A new asymmetric synthesis of several hydroxy N,O-heterobicyclic octanes is described in this paper. The synthesis employed Salen catalysed epoxide ring opening of the starting material meso-cyclohexene followed by the azide reduction and NBoc protection of (1S,6S)-6-azido-3-cyclohexenol, allylic hydroxylation and lactonization with final carbonyl reduction to produce hydroxy N,O-heterobicyclic octane. © 2022 Malaysian Institute of Chemistry. All rights reserved. Malaysian Institute of Chemistry 15112292 English Conference paper |
| author |
Sharoman N.S.; Imran S.; Ali M.T.M. |
| spellingShingle |
Sharoman N.S.; Imran S.; Ali M.T.M. Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes |
| author_facet |
Sharoman N.S.; Imran S.; Ali M.T.M. |
| author_sort |
Sharoman N.S.; Imran S.; Ali M.T.M. |
| title |
Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes |
| title_short |
Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes |
| title_full |
Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes |
| title_fullStr |
Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes |
| title_full_unstemmed |
Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes |
| title_sort |
Asymmetric Synthesis of Hydroxy N,O-Heterobicyclic Octanes |
| publishDate |
2022 |
| container_title |
Malaysian Journal of Chemistry |
| container_volume |
24 |
| container_issue |
2 |
| doi_str_mv |
|
| url |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133513339&partnerID=40&md5=a1bf76ed85bd8ee08de14a84a9df42c3 |
| description |
A new asymmetric synthesis of several hydroxy N,O-heterobicyclic octanes is described in this paper. The synthesis employed Salen catalysed epoxide ring opening of the starting material meso-cyclohexene followed by the azide reduction and NBoc protection of (1S,6S)-6-azido-3-cyclohexenol, allylic hydroxylation and lactonization with final carbonyl reduction to produce hydroxy N,O-heterobicyclic octane. © 2022 Malaysian Institute of Chemistry. All rights reserved. |
| publisher |
Malaysian Institute of Chemistry |
| issn |
15112292 |
| language |
English |
| format |
Conference paper |
| accesstype |
|
| record_format |
scopus |
| collection |
Scopus |
| _version_ |
1809677892810964992 |