Design and Development of Levodopa Loaded Polymeric Nanoparticles for Intranasal Delivery

QR Code

Design and Development of Levodopa Loaded Polymeric Nanoparticles for Intranasal Delivery

Intranasal delivery is an alternative administration route to deliver levodopa (L-Dopa) to the brain. This drug delivery route offers high drug permeability across the nasal epithelium and rapid absorption into the central nervous system (CNS) while bypassing first-pass metabolism. In this study, we...

Full description

Bibliographic Details
Published in:	Pharmaceuticals
Main Author:	Ahmad M.Z.; Sabri A.H.B.; Anjani Q.K.; Domínguez-Robles J.; Abdul Latip N.; Hamid K.A.
Format:	Article
Language:	English
Published:	MDPI 2022
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127558295&doi=10.3390%2fph15030370&partnerID=40&md5=41584bf009fcec2ddb97b06ccbbf6acc

Similar Items

Tip loaded cyclodextrin-carvedilol complexes microarray patches
by: Anjani Q.K.; Sabri A.H.B.; Hamid K.A.; Moreno-Castellanos N.; Li H.; Donnelly R.F.
Published: (2023)

Intestinal Absorption Study: Challenges and Absorption Enhancement Strategies in Improving Oral Drug Delivery
by: Azman M.; Sabri A.H.; Anjani Q.K.; Mustaffa M.F.; Hamid K.A.
Published: (2022)

Primaquine and chloroquine nano-sized solid dispersion-loaded dissolving microarray patches for the improved treatment of malaria caused by Plasmodium vivax
by: Anjani Q.K.; Volpe-Zanutto F.; Hamid K.A.; Sabri A.H.B.; Moreno-Castellano N.; Gaitán X.A.; Calit J.; Bargieri D.Y.; Donnelly R.F.
Published: (2023)

In Vitro Permeation Studies on Carvedilol Containing Dissolving Microarray Patches Quantified Using a Rapid and Simple HPLC-UV Analytical Method
by: Anjani Q.K.; Sabri A.H.B.; McGuckin M.B.; Li H.; Hamid K.A.; Donnelly R.F.
Published: (2022)

Ischemic brain treated with 6-gingerol loaded mucoadhesive nanoemulsion via intranasal delivery and their comparative pharmacokinetic effect in brain
by: Ahmad N.; Ahmad R.; Amir M.; Alam M.A.; Almakhamel M.Z.; Ali A.; Ahmad A.; Ashraf K.
Published: (2021)

Chitosan-Based Nanocarriers for Pulmonary and Intranasal Drug Delivery Systems: A Comprehensive Overview of their Applications
by: Alwahsh, et al.
Published: (2024)

Chitosan-Based Nanocarriers for Pulmonary and Intranasal Drug Delivery Systems: A Comprehensive Overview of their Applications
by: Alwahsh W.; Sahudin S.; Alkhatib H.; Bostanudin M.F.; Alwahsh M.
Published: (2024)

Comparison of virus-capsid mimicking biologic-shell based versus polymeric-shell nanoparticles for enhanced oral insulin delivery
by: Cui Z.; Cui S.; Qin L.; An Y.; Zhang X.; Guan J.; Wong T.W.; Mao S.
Published: (2023)

Pharmacological evaluation of nasal delivery of selegiline hydrochloride-loaded thiolated chitosan nanoparticles for the treatment of depression
by: Singh D.; Rashid M.; Hallan S.S.; Mehra N.K.; Prakash A.; Mishra N.
Published: (2016)

Natural Polymeric Composites Derived from Animals, Plants, and Microbes for Vaccine Delivery and Adjuvant Applications: A Review
by: Nordin A.H.; Husna S.M.N.; Ahmad Z.; Nordin M.L.; Ilyas R.A.; Azemi A.K.; Ismail N.; Siti N.H.; Ngadi N.; Azami M.S.M.; Mohamad Norpi A.S.; Reduan M.F.H.; Osman A.Y.; Pratama D.A.O.A.; Nabgan W.; Shaari R.
Published: (2023)

Synthesis of chitosan-gold nanoparticles for drug delivery
by: Yazid H.; Yassin A.M.; Ruslan A.Z.; Alias S.H.; Adnan R.; Md Jani A.M.
Published: (2014)

In vitro evaluation of the inhalable quercetin loaded nanoemulsion for pulmonary delivery
by: Arbain N.H.; Salim N.; Masoumi H.R.F.; Wong T.W.; Basri M.; Abdul Rahman M.B.
Published: (2019)

Advanced strategies for combinational immunotherapy of cancer based on polymeric nanomedicines
by: You K.; Wang Q.; Osman M.S.; Kim D.; Li Q.; Feng C.; Wang L.; Yang K.
Published: (2024)

Polymeric and non-polymeric nanofiber of Cinnamaldehyde from Cinnamon oil (Cinnamomum zeylanicum)
by: Moreta S.; Cahyono E.; Affandi N.D.N.; Fadil F.; Kurniawan C.
Published: (2020)

Optimization of quercetin loaded palm oil ester based nanoemulsion formulation for pulmonary delivery
by: Arbain N.H.; Salim N.; Wui W.T.; Basri M.; Rahman M.B.A.
Published: (2018)

Overcoming colloidal nanoparticle aggregation in biological milieu for cancer therapeutic delivery: Perspectives of materials and particle design
by: Lim S.H.; Wong T.W.; Tay W.X.
Published: (2024)

Polymeric/ceramic membranes for water reuse
by: Alias N.H.; Aziz M.H.A.; Adam M.R.; Aizudin M.; Ang E.H.
Published: (2023)

Polymeric membranes for natural gas sweetening
by: Ahmad A.L.; Zainuddin M.I.F.; Shah Buddin M.M.H.
Published: (2024)

Prednisolone-Loaded Solid Lipid Nanoparticles: Preformulation Studies and Physicochemical Characterisation
by: Zainudin A.N.M.; Shafri A.S.M.; Naharudin I.; Affandi M.M.R.M.M.; Anuar N.K.
Published: (2024)

Enhancement of Skin Permeation and Penetration of β-Arbutin Fabricated in Chitosan Nanoparticles as the Delivery System
by: Sahudin S.; Sahrum Ayumi N.; Kaharudin N.
Published: (2022)

Radiation Induced Polymerization of N-isopropyl acrylamide Polymer Gel Characterized by Raman Laser
by: Adenan M.Z.
Published: (2020)

Development and characterisation of ibuprofen-loaded nanoemulsion with enhanced oral bioavailability
by: Anuar N.; Sabri A.H.; Bustami Effendi T.J.; Abdul Hamid K.
Published: (2020)

Investigating and Modeling Ageing Effects on Polymeric Insulator Electrical Properties
by: Salem A.A.; Alawady A.A.; Lau K.Y.; Rahiman W.; Abdul-Malek Z.; Al-Gailani S.A.; Al-Ameri S.M.; Ali E.; Ghoneim S.S.M.
Published: (2023)

Distinguishing relaxation dynamics in transiently crosslinked polymeric networks
by: Tan C.S.Y.; Agmon G.; Liu J.; Hoogland D.; Janeček E.-R.; Appel E.A.; Scherman O.A.
Published: (2017)

Signal Improvement on Fibre Optic Evanescent Wave Sensor Based Polymeric Sensitive Coating of Chitosan-Agarose Hydrogel
by: Akashah M.H.N.; Makhsin S.R.; Rani R.A.; Saad N.H.; Razak K.A.; Gardner P.; Scully P.J.
Published: (2023)

Electrochemical Deposition of Cu-Nanoparticle-Loaded CdSe/TiO2 Nanotube Nanostructure as Photoelectrode
by: Ayal A.K.; Hashim A.K.; Mohammed A.M.; Farhan A.M.; Holi A.M.; Lim Y.-C.
Published: (2021)

Polymerization of lactide to polylactic acid by using homogenous and heterogenous catalysts
by: Ibrahim N.; Mohamed A.S.
Published: (2019)

Design and development of novel hyaluronate-modified nanoparticles for combo-delivery of curcumin and alendronate: fabrication, characterization, and cellular and molecular evidences of enhanced bone regeneration
by: Dong J.; Tao L.; Abourehab M.A.S.; Hussain Z.
Published: (2018)

A comparison of characteristics between food delivery riders with and without traffic crash experience during delivery in Malaysia
by: Rusli R.; Mohammad M.Z.; Azreena Kamaluddin N.; Bakar H.; Hafzi Md Isa M.
Published: (2022)

The State of the Art of Natural Polymer Functionalized Fe3O4 Magnetic Nanoparticle Composites for Drug Delivery Applications: A Review
by: Nordin A.H.; Ahmad Z.; Husna S.M.N.; Ilyas R.A.; Azemi A.K.; Ismail N.; Nordin M.L.; Ngadi N.; Siti N.H.; Nabgan W.; Norfarhana A.S.; Azami M.S.M.
Published: (2023)

Radiation-induced admicellar polymerization of methacrylate acid for pH responsive cellulose nanofibrils
by: Hakimi N.M.F.; Mohamad S.F.; Al Edrus S.S.O.; Antov P.; Fatriasari W.; Abdan K.; Lee S.H.
Published: (2024)

Potential of Exosomes as Multifunctional Nanocarriers for Targeted Drug Delivery
by: Al-Ani S.A.; Lee Q.Y.; Maheswaran D.; Sin Y.M.; Loh J.S.; Foo J.B.; Hamzah S.; Ng J.F.; Tan L.K.S.
Published: (2024)

Influences of co-polymerization 1-vinylimidazole onto γ-irradiated poly(vinylidene flouride) membranes
by: Lepit A.; Aini N.A.; Jaafar N.K.; Hashim N.; Ali A.M.M.; Dahlan K.Z.M.; Yahya M.Z.A.
Published: (2012)

Morphological Characterization of Silver Nanowires (AgNWs)-Embedded Polymeric Film for Flexible Wearable Antenna
by: Osman M.S.; Abd Halim N.H.; Khairudin K.; Abu Bakar A.; Razali A.R.; Fathullah M.; Abdul Razak A.K.; Akbar M.S.
Published: (2023)

Biomass Lignin Integrated Polymeric Carbon Nitride for Boosted Photocatalytic Hydrogen and Oxygen Evolution Reactions
by: Hayat A.; Sohail M.; Hamdy M.S.; Amin M.A.; Alharthi S.; Taha T.A.; Rahman M.M.; Palamanit A.; Khan J.; Mane S.K.B.; Nawawi W.I.
Published: (2022)

Hyaluronic acid decorated tacrolimus-loaded nanoparticles: Efficient approach to maximize dermal targeting and anti-dermatitis efficacy
by: Zhuo F.; Abourehab M.A.S.; Hussain Z.
Published: (2018)

A Straightforward Approach of Chemical Oxidative Polymerization to Synthesis Polyaniline for The Conductive Fabrics Applications
by: Aizamddin M.F.; Mahat M.M.; Nawawi M.A.
Published: (2024)

A Framework of an Interior Design Work Delivery Process
by: Mustapha A.A.; Mohamad M.F.; Noorhani N.M.A.
Published: (2021)

Liposome-based drug and vaccine delivery system in veterinary application: Recent advancement and future trends - A review
by: Sidek N.A.M.; Norpi A.S.M.; Mohamed M.; Ramli M.Z.; Nordin A.H.; Shaharulnizim N.; Mohamad M.A.; Hambali K.A.; Razik M.A.; Ismail N.; Nordin M.L.; Azemi A.K.
Published: (2024)

Enhanced photocatalytic overall water splitting from an assembly of donor-π-acceptor conjugated polymeric carbon nitride
by: Hayat A.; Sohail M.; Anwar U.; Taha T.A.; El-Nasser K.S.; Alenad A.M.; Al-Sehemi A.G.; Ahmad Alghamdi N.; Al-Hartomy O.A.; Amin M.A.; Alhadhrami A.; Palamanit A.; Mane S.K.B.; Nawawi W.I.; Ajmal Z.
Published: (2022)