Site of Metabolism (SOM) Predictions for Centella asiatica and Orthosiphon stamineus Marker Compounds with CYP3A4 Using a Molecular Docking Approach

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Site of Metabolism (SOM) Predictions for Centella asiatica and Orthosiphon stamineus Marker Compounds with CYP3A4 Using a Molecular Docking Approach

The human liver enzyme CYP3A4 plays an important role in the biotransformation of xenobiotics from herbs to harmless and excretable metabolites. However, CYP3A4 catalytic activity may also produce more toxic metabolites. Predicting sites of metabolism (SOMs) in the xenobiotics may prevent unwanted C...

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Bibliographic Details
Published in:	Malaysian Journal of Chemistry
Main Author:	Ridhwan M.J.M.; Bakar S.I.A.; Ismail N.H.
Format:	Article
Language:	English
Published:	Malaysian Institute of Chemistry 2021
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127480950&doi=10.55373%2fMJCHEM.V23I4.1188&partnerID=40&md5=04960f3397adebc4cc3a104774a1a5dd

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