A Comprehensive Analysis of Human CYP3A4 Crystal Structures as a Potential Tool for Molecular Docking-Based Site of Metabolism and Enzyme Inhibition Studies

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A Comprehensive Analysis of Human CYP3A4 Crystal Structures as a Potential Tool for Molecular Docking-Based Site of Metabolism and Enzyme Inhibition Studies

The notable ability of human liver cytochrome P450 3A4 (CYP3A4) to metabolize diverse xenobiotics encourages researchers to explore in-depth the mechanism of enzyme action. Numerous CYP3A4 protein crystal structures have been deposited in protein data bank (PDB) and are majorly used in molecular doc...

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Bibliographic Details
Published in:	Journal of Computational Biophysics and Chemistry
Main Author:	Ridhwan M.J.M.; Bakar S.I.A.; Latip N.A.; Ghani N.A.; Ismail N.H.
Format:	Review
Language:	English
Published:	World Scientific 2022
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125812608&doi=10.1142%2fS2737416522300012&partnerID=40&md5=fcdc51c6352c690143b5395fc6cedd3c

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