A Comprehensive Analysis of Human CYP3A4 Crystal Structures as a Potential Tool for Molecular Docking-Based Site of Metabolism and Enzyme Inhibition Studies
The notable ability of human liver cytochrome P450 3A4 (CYP3A4) to metabolize diverse xenobiotics encourages researchers to explore in-depth the mechanism of enzyme action. Numerous CYP3A4 protein crystal structures have been deposited in protein data bank (PDB) and are majorly used in molecular doc...
| Published in: | Journal of Computational Biophysics and Chemistry |
|---|---|
| Main Author: | |
| Format: | Review |
| Language: | English |
| Published: |
World Scientific
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125812608&doi=10.1142%2fS2737416522300012&partnerID=40&md5=fcdc51c6352c690143b5395fc6cedd3c |