Synthesis, molecular docking, and antimalarial activity of hybrid 4-aminoquinoline-pyrano[2,3-c]pyrazole derivatives

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Synthesis, molecular docking, and antimalarial activity of hybrid 4-aminoquinoline-pyrano[2,3-c]pyrazole derivatives

Widespread resistance of Plasmodium falciparum to current artemisinin-based combination therapies necessitate the discovery of new medicines. Pharmacophoric hybridization has become an alternative for drug resistance that lowers the risk of drug–drug adverse interactions. In this study, we synthesiz...

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Bibliographic Details
Published in:	Pharmaceuticals
Main Author:	Shamsuddin M.A.; Ali A.H.; Zakaria N.H.; Mohammat M.F.; Hamzah A.S.; Shaameri Z.; Lam K.W.; Mark-Lee W.F.; Agustar H.K.; Abd Razak M.R.M.; Latip J.; Hassan N.I.
Format:	Article
Language:	English
Published:	MDPI 2021
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119887130&doi=10.3390%2fph14111174&partnerID=40&md5=66c84c69573c3ccc9d9d0c4200d6f7dd

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