Synthesis of new 1,2-disubstituted benzimidazole analogs as potent inhibitors of β-Glucuronidase and in silico study

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Synthesis of new 1,2-disubstituted benzimidazole analogs as potent inhibitors of β-Glucuronidase and in silico study

New benzimidazole analogues (1–18) were synthesized and characterized through different spectroscopic techniques such as 1H NMR, 13C NMR and HREI-MS. All analogues were screened for β-glucuronidase inhibitory potential. All analogues showed varied degree of inhibitory potentials with IC50 values ran...

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Bibliographic Details
Published in:	Arabian Journal of Chemistry
Main Author:	Taha M.; Ahmad Khan A.; Rahim F.; Imran S.; Salahuddin M.; Uddin N.; Mohammed Khan K.; Adnan Ali Shah S.; Zafar A.; Amiruddin Zakaria Z.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2022
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118560785&doi=10.1016%2fj.arabjc.2021.103505&partnerID=40&md5=86c929f9aa372ce6e6b7f7706329ed8a

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