Untargeted serum metabolites profiling in high-fat diet mice supplemented with enhanced palm tocotrienol-rich fraction using UHPLC-MS
Excessive high fat dietary intake promotes risk of developing non-alcoholic fatty liver disease (NAFLD) and predisposed with oxidative stress. Palm based tocotrienol-rich fraction (TRF) has been reported able to ameliorate oxidative stress but exhibited poor bioavailability. Thus, we investigated wh...
Published in: | Scientific Reports |
---|---|
Main Author: | Goon D.E.; Ab-Rahim S.; Mohd Sakri A.H.; Mazlan M.; Tan J.K.; Abdul Aziz M.; Mohd Noor N.; Ibrahim E.; Sheikh Abdul Kadir S.H. |
Format: | Article |
Language: | English |
Published: |
Nature Research
2021
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117921555&doi=10.1038%2fs41598-021-00454-9&partnerID=40&md5=f93c826ff64544ef8e2ca0e92f8b19c5 |
Similar Items
-
Palm tocotrienol rich fraction with palm kernel oil supplementation prevents development of liver steatosis in high fat diet ICR mice
by: Goon M.D.M.E.; Zulkanain N.I.; Kadir S.H.S.A.; Rahim S.A.; Mazlan M.; Latip N.A.; Aziz M.A.; Noor N.M.
Published: (2022) -
Palm-based tocotrienol-rich fraction (TRF) supplementation modulates cardiac sod1 expression, fxr target gene expression, and tauro-conjugated bile acid levels in aleptinemic mice fed a high-fat diet
by: Md Shahrulnizam N.A.N.; Mohd Efendy Goon M.D.; Ab Rahim S.; Lew S.W.; Sheikh Abdul Kadir S.H.; Ibrahim E.
Published: (2024) -
Effects of Aging and Tocotrienol-Rich Fraction Supplementation on Brain Arginine Metabolism in Rats
by: Mazlan M.; Hamezah H.S.; Taridi N.M.; Jing Y.; Liu P.; Zhang H.; Wan Ngah W.Z.; Damanhuri H.A.
Published: (2017) -
Palm tocotrienol-rich fraction supplementation suppressed stress-induced gastric oxidative stress in rats
by: Kamisah Y.; Ibrahim A.A.I.; Nafeeza M.I.; Nur-Azlina M.F.
Published: (2011) -
The differential metabolite profiles of acute lymphoblastic leukaemic patients treated with 6-mercaptopurine using untargeted metabolomics approach
by: Bannur Z.; Teh L.K.; Hennesy T.; Rosli W.R.W.; Mohamad N.; Nasir A.; Ankathil R.; Zakaria Z.A.; Baba A.; Salleh M.Z.
Published: (2014)