Asymmetric Synthesis of N,O-Heterobicyclic Octanes and (−)-Geissman-Waiss Lactone

A short, asymmetric synthesis of tetrahydro-2H-furo[3,2-b]pyrrole derivatives and (−)-Geissman-Waiss lactone starting frommeso-cyclohexadiene epoxide is described. Pivotal transformations in the developed synthetic procedure include asymmetric epoxide ring opening to install the requisite 1S,5Sstere...

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Bibliographic Details
Published in:ACS Omega
Main Author: Ali M.T.M.; Husin Z.M.; Macabeo A.P.G.
Format: Article
Language:English
Published: American Chemical Society 2021
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115987386&doi=10.1021%2facsomega.1c03251&partnerID=40&md5=ba02bcad1df9b17b1fd51e8216f8757f