Comprehensive analysis of mutations and clonal evolution patterns in a cohort of patients with cytogenetically normal acute myeloid leukemia

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Comprehensive analysis of mutations and clonal evolution patterns in a cohort of patients with cytogenetically normal acute myeloid leukemia

Background: Relapsed acute myeloid leukemia (AML) is associated with the acquisition of additional somatic mutations which are thought to drive phenotypic adaptability, clonal selection and evolution of leukemic clones during treatment. We performed high throughput exome sequencing of matched presen...

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Bibliographic Details
Published in:	Molecular Cytogenetics
Main Author:	Mat Yusoff Y.; Ahid F.; Abu Seman Z.; Abdullah J.; Kamaluddin N.R.; Esa E.; Zakaria Z.
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2021
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115642717&doi=10.1186%2fs13039-021-00561-2&partnerID=40&md5=2df67e2c9fb6c62b4fb2d74fdcb54952

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