Discovery of polymethoxyflavones as potential cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX) and phosphodiesterase 4B (PDE4B) inhibitors

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Discovery of polymethoxyflavones as potential cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX) and phosphodiesterase 4B (PDE4B) inhibitors

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed to treat inflammatory-related diseases, pain and fever. However, the prolong use of traditional NSAIDs leads to undesirable side effects such as gastric, ulceration, and renal toxicity due to lack of selectivity toward respective t...

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Bibliographic Details
Published in:	Journal of Receptors and Signal Transduction
Main Author:	Md Idris M.H.; Mohd Amin S.N.; Mohd Amin S.N.; Wibowo A.; Zakaria Z.A.; Shaameri Z.; Hamzah A.S.; Selvaraj M.; Teh L.K.; Salleh M.Z.
Format:	Article
Language:	English
Published:	Taylor and Francis Ltd. 2022
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111692224&doi=10.1080%2f10799893.2021.1951756&partnerID=40&md5=cafd907b47055701447a315ed2411d8a

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