Synthesis, in vitro antiurease, in vivo antinematodal activity of quinoline analogs and their in-silico study

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Synthesis, in vitro antiurease, in vivo antinematodal activity of quinoline analogs and their in-silico study

Synthesis of quinoline analogs and their urease inhibitory activities with reference to the standard drug, thiourea (IC50 = 21.86 ± 0.40 µM) are presented in this study. The inhibitory activity range is (IC50 = 0.60 ± 0.01 to 24.10 ± 0.70 µM) which displayed that it is most potent class of urease in...

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Bibliographic Details
Published in:	Bioorganic Chemistry
Main Author:	Zaman K.; Rahim F.; Taha M.; Sajid M.; Hayat S.; Nawaz M.; Salahuddin M.; Iqbal N.; Khan N.U.; Shah S.A.A.; Farooq R.K.; Bahadar A.; Wadood A.; Khan K.M.
Format:	Article
Language:	English
Published:	Academic Press Inc. 2021
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111271761&doi=10.1016%2fj.bioorg.2021.105199&partnerID=40&md5=014dc8e6fd0be2edc556481e1cc07e93

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