Synthesis, in vitro antiurease, in vivo antinematodal activity of quinoline analogs and their in-silico study
Synthesis of quinoline analogs and their urease inhibitory activities with reference to the standard drug, thiourea (IC50 = 21.86 ± 0.40 µM) are presented in this study. The inhibitory activity range is (IC50 = 0.60 ± 0.01 to 24.10 ± 0.70 µM) which displayed that it is most potent class of urease in...
Published in: | Bioorganic Chemistry |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Academic Press Inc.
2021
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111271761&doi=10.1016%2fj.bioorg.2021.105199&partnerID=40&md5=014dc8e6fd0be2edc556481e1cc07e93 |