Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2...
| Published in: | Scientific Reports |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Nature Research
2021
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110729100&doi=10.1038%2fs41598-021-93964-5&partnerID=40&md5=1ebc90baea25f6552983f2158c1b01a6 |
| Summary: | We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2 and 8 Gy absorbed doses. The lead shielding was fabricated into a cuboid shape with a canal on the top and a hole on the vertical side for the beam path. Respective deliveries doses of 28 and 75 Gy from gamma-cell were used to achieve 2 and 8 Gy absorbed doses at the tumour sites. © 2021, The Author(s). |
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| ISSN: | 20452322 |
| DOI: | 10.1038/s41598-021-93964-5 |