The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review

Speckle tracking echocardiography (STE) has gained importance in the evaluation of adult inherited cardiomyopathies, but its utility in children is not well characterized. We conducted a systematic review to evaluate the role of STE in pediatric inherited cardiomyopathies. PubMed, EMBASE, Web of Sci...

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Published in:Diagnostics
Main Author: Dorobantu D.M.; Wadey C.A.; Amir N.H.; Stuart A.G.; Williams C.A.; Pieles G.E.
Format: Review
Language:English
Published: Multidisciplinary Digital Publishing Institute (MDPI) 2021
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109027725&doi=10.3390%2fdiagnostics11040635&partnerID=40&md5=0614ab9625145abf0135b8359a637bb9
id 2-s2.0-85109027725
spelling 2-s2.0-85109027725
Dorobantu D.M.; Wadey C.A.; Amir N.H.; Stuart A.G.; Williams C.A.; Pieles G.E.
The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review
2021
Diagnostics
11
4
10.3390/diagnostics11040635
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109027725&doi=10.3390%2fdiagnostics11040635&partnerID=40&md5=0614ab9625145abf0135b8359a637bb9
Speckle tracking echocardiography (STE) has gained importance in the evaluation of adult inherited cardiomyopathies, but its utility in children is not well characterized. We conducted a systematic review to evaluate the role of STE in pediatric inherited cardiomyopathies. PubMed, EMBASE, Web of Science, Scopus, CENTRAL and CINAHL databases were searched up to May 2020, for terms related to inherited cardiomyopathies and STE. Included were dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), left ventricular non-compaction (LVNC) and arrhyth-mogenic cardiomyopathy (ACM). A total of 14 cohorts were identified, of which six were in DCM, four in HCM, three in LVNC and one in ACM. The most commonly reported STE measurements were left ventricular longitudinal strain (Sl), circumferential strain (Sc), radial strain (Sr) and rota-tion/torsion/twist. Sl, Sc and were abnormal in all DCM and LVNC cohorts, but not in all HCM. Apical rotation and twist/torsion were increased in HCM, and decreased in LVNC. Abnormal STE parameters were reported even in cohorts with normal non-STE systolic/diastolic measurements. STE in childhood cardiomyopathies can detect early changes which may not be associated with changes in cardiac function detectable by non-STE methods. Longitudinal and circumferential strain should be introduced in the cardiomyopathy echocardiography protocol, reflecting current practice in adults. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Multidisciplinary Digital Publishing Institute (MDPI)
20754418
English
Review
All Open Access; Gold Open Access
author Dorobantu D.M.; Wadey C.A.; Amir N.H.; Stuart A.G.; Williams C.A.; Pieles G.E.
spellingShingle Dorobantu D.M.; Wadey C.A.; Amir N.H.; Stuart A.G.; Williams C.A.; Pieles G.E.
The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review
author_facet Dorobantu D.M.; Wadey C.A.; Amir N.H.; Stuart A.G.; Williams C.A.; Pieles G.E.
author_sort Dorobantu D.M.; Wadey C.A.; Amir N.H.; Stuart A.G.; Williams C.A.; Pieles G.E.
title The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review
title_short The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review
title_full The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review
title_fullStr The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review
title_full_unstemmed The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review
title_sort The role of speckle tracking echocardiography in the evaluation of common inherited cardiomyopathies in children and adolescents: A systematic review
publishDate 2021
container_title Diagnostics
container_volume 11
container_issue 4
doi_str_mv 10.3390/diagnostics11040635
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109027725&doi=10.3390%2fdiagnostics11040635&partnerID=40&md5=0614ab9625145abf0135b8359a637bb9
description Speckle tracking echocardiography (STE) has gained importance in the evaluation of adult inherited cardiomyopathies, but its utility in children is not well characterized. We conducted a systematic review to evaluate the role of STE in pediatric inherited cardiomyopathies. PubMed, EMBASE, Web of Science, Scopus, CENTRAL and CINAHL databases were searched up to May 2020, for terms related to inherited cardiomyopathies and STE. Included were dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), left ventricular non-compaction (LVNC) and arrhyth-mogenic cardiomyopathy (ACM). A total of 14 cohorts were identified, of which six were in DCM, four in HCM, three in LVNC and one in ACM. The most commonly reported STE measurements were left ventricular longitudinal strain (Sl), circumferential strain (Sc), radial strain (Sr) and rota-tion/torsion/twist. Sl, Sc and were abnormal in all DCM and LVNC cohorts, but not in all HCM. Apical rotation and twist/torsion were increased in HCM, and decreased in LVNC. Abnormal STE parameters were reported even in cohorts with normal non-STE systolic/diastolic measurements. STE in childhood cardiomyopathies can detect early changes which may not be associated with changes in cardiac function detectable by non-STE methods. Longitudinal and circumferential strain should be introduced in the cardiomyopathy echocardiography protocol, reflecting current practice in adults. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
publisher Multidisciplinary Digital Publishing Institute (MDPI)
issn 20754418
language English
format Review
accesstype All Open Access; Gold Open Access
record_format scopus
collection Scopus
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