Evaluating the effect of RUNX1/ETO expression on mutagenesis at the NPM1 locus using flow cytometry

QR Code

Evaluating the effect of RUNX1/ETO expression on mutagenesis at the NPM1 locus using flow cytometry

Introduction: The high number of mutations observed in many cancers including acute myeloid leukemia (AML) led to the mutator phenotype hypothesis, which suggests that an early initiating mutational event acts as a driver for the acquisition of additional mutations which eventually lead to transform...

Full description

Bibliographic Details
Published in:	Malaysian Journal of Medicine and Health Sciences
Main Author:	Ahid F.; Abd Rahman A.Z.; Ismail A.
Format:	Article
Language:	English
Published:	Universiti Putra Malaysia Press 2021
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108962324&partnerID=40&md5=41ecfe4780a6538469b71e4e1fbdeb9c

Similar Items

Increased RUNX1 mutations in breast cancer disease progression
by: Ariffin N.S.
Published: (2024)

Increased RUNX1 mutations in breast cancer disease progression
by: Ariffin, et al.
Published: (2024)

Whole-exome sequencing of ETV6/RUNX1 in four childhood acute lymphoblastic leukaemia cases
by: Zakaria Z.; Othman N.; Ismail A.; Kamaluddin N.R.; Esa E.; Rahman E.J.A.; Yusoff Y.M.; Fauzi F.M.; Keoh T.S.
Published: (2017)

Development of flow cytometry analysis on measuring tumour immune microenvironment (TIME) in mice bearing EMT6 tumour model
by: Ibahim M.J.; Hasani N.A.H.; Sham F.R.; Omar E.; Fuad S.B.S.A.; Karim M.K.A.; Hasan N.
Published: (2022)

Differential gene expression of blood-based ABCA9, CNOT8, SESN1, UCP3, MAP2K1 and DDIT4 in Alzheimer’s disease
by: Samsudin A.Z.; Ramasamy K.; Lim S.M.; Chin A.V.; Tan M.P.; Kamaruzzaman S.B.; Ibrahim B.; Majeed A.B.A.
Published: (2023)

SYMPTOMS OF DEPRESSION AMONG HEALTH SCIENCES STUDENTS AND ITS RELATION TO LOCUS OF CONTROL
by: Jasdi N.F.S.; Rahman P.A.
Published: (2023)

Different concentrations of nivolumab reduce PD-1 expression but not tumour growth in an EMT6 mouse model
by: Sham, et al.
Published: (2024)

The intergenerational effects of oligomeric proanthocyanidins on expression of Sult2a2, Sult2al1 and Sult2a1 in Bisphenol A-exposed male rats
by: Siti-Aishah Z.; Razif D.; Mohd Hafizi M.; Fatin N.O.; Nur Hilwani I.; Fatin Nadzirah Z.; Nina Keterina H.; Mastura A.M.
Published: (2020)

How do locus of control influence business and personal success? The mediating effects of entrepreneurial competency
by: Hamzah M.I.; Othman A.K.
Published: (2023)

Differential expression of cytokine genes in THP-1-derived macrophages infected with mild and virulence strains of Shigella flexneri 2a
by: Shabani N.R.M.; Mokhtar M.; Leow C.Y.; Lean Q.Y.; Chuah C.; Singh K.K.B.
Published: (2020)

Baeckea frutescens L. Promotes wound healing by upregulating expression of TGF-β, IL-1 β, VEGF and MMP-2
by: Safwan Kamarazaman I.; Sui Kiong L.; Nik Hasan M.K.; Basherudin N.; Mohd Kasim N.A.; Ali A.A.; Ramli S.; Maniam S.; Johari James R.; Rojsitthisak P.; Halim H.
Published: (2024)

Baeckea frutescens L. Promotes wound healing by upregulating expression of TGF-β, IL-1 β, VEGF and MMP-2
by: Kamarazaman, et al.
Published: (2024)

Identifying sequence maps or locus to represent the genetic structure or genome standard of styling DNA in automotive design
by: Zainal Abidin S.; Othman A.; Shamsuddin Z.; Samsudin Z.; Hassan H.; Wan Mohamed W.A.
Published: (2016)

Palm-based tocotrienol-rich fraction (TRF) supplementation modulates cardiac sod1 expression, fxr target gene expression, and tauro-conjugated bile acid levels in aleptinemic mice fed a high-fat diet
by: Md Shahrulnizam N.A.N.; Mohd Efendy Goon M.D.; Ab Rahim S.; Lew S.W.; Sheikh Abdul Kadir S.H.; Ibrahim E.
Published: (2024)

Tocotrienol Rich Fraction Supplementation Modulate Brain Hippocampal Gene Expression in APPswe/PS1dE9 Alzheimer's Disease Mouse Model
by: Nasri W.N.W.; Makpol S.; Mazlan M.; Tooyama I.; Ngah W.Z.W.; Damanhuri H.A.
Published: (2019)

Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice
by: Musa M.; Wilson K.; Sun L.; Mulay A.; Bingle L.; Marriott H.M.; LeClair E.E.; Bingle C.D.
Published: (2012)

Overexpression of Bactericidal/Permeability-Increasing Fold-Containing Family BPIFB1 in Gastric Cancer Cells Leads to Differential Expression of E-Cadherin and MUC5AC
by: Nor Azlin Safina Abdul Aziz; Musa M.; Kadir S.H.S.A.; Karim Z.R.A.; Hasani N.A.H.
Published: (2023)

Mathematical modeling and experiment verification for the Solid oxide Fuel Cell Mn1.5Co1.5O4 interconnect coating
by: Kang Huai T.; Lowrance Y.; Farhana Abd Rahman N.; Asyikin Yusop U.; Abd Rahman H.; Jaidi Z.; Faizal Tukimon M.; Saifulddin Mohd Azami M.
Published: (2024)

Mathematical modeling and experiment verification for the Solid oxide Fuel Cell Mn1.5Co1.5O4 interconnect coating
by: Huai, et al.
Published: (2024)

Illegitimacy and sibship assignments in oil palm (Elaeis guineensis Jacq.) half-sib families using single locus DNA microsatellite markers
by: Hama-Ali E.O.; Alwee S.S.R.S.; Tan S.G.; Panandam J.M.; Ling H.C.; Namasivayam P.; Peng H.B.
Published: (2015)

Evaluation of Glutathione S-transferases Expression as Biomarkers by Heavy Metals in Geloina expansa from Sepang Besar River, Selangor, Malaysia
by: Wakid, et al.
Published: (2024)

Evaluation of Machine Learning Models for Breast Cancer Detection in Microarray Gene Expression Profiles
by: Abdullah M.N.; Wah Y.B.
Published: (2024)

Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides
by: Yadav S.; Lim S.M.; Ramasamy K.; Vasudevan M.; Shah S.A.A.; Mathur A.; Narasimhan B.
Published: (2018)

Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency - a systematic review and integrated bioinformatic analysis
by: Faizal, et al.
Published: (2024)

Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency - a systematic review and integrated bioinformatic analysis
by: Faizal A.M.; Elias M.H.; Jin N.M.; Abu M.A.; Syafruddin S.E.; Zainuddin A.A.; Suzuki N.; Karim A.K.A.
Published: (2024)

Synthesis of halogenated [1,1′-biphenyl]-4-yl benzoate and [1,1′:3′,1″- terphenyl]-4′-yl benzoate by palladium catalyzed cascade C–C coupling and structural analysis through computational approach
by: Imran H.M.; Rasool N.; Kanwal I.; Hashmi M.A.; Altaf A.A.; Ahmed G.; Malik A.; Kausar S.; Ud-Din Khan S.; Ahmad A.; Ali Shah S.A.
Published: (2020)

Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 assimilate cholesterol and modulate ABCA1, CD36, NPC1L1 and SCARB1 in vitro
by: Lim F.T.; Lim S.M.; Ramasamy K.
Published: (2017)

BPIFB1 (LPLUNC1) is upregulated in cystic fibrosis lung disease
by: Bingle L.; Wilson K.; Musa M.; Araujo B.; Rassl D.; Wallace W.A.; LeClair E.E.; Mauad T.; Zhou Z.; Mall M.A.; Bingle C.D.
Published: (2012)

Mitragynine, an euphoric compound inhibits hERG1a/1b channel current and upregulates the complexation of hERG1a-Hsp90 in HEK293-hERG1a/1b cells
by: Tay Y.L.; Amanah A.; Adenan M.I.; Wahab H.A.; Tan M.L.
Published: (2019)

Synthesis, antimicrobial and cytotoxic evaluation of 4-(1-aryl-5-halo-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides
by: Kumar M.; Narasimhan B.; Ramasamy K.; Mani V.; Mishra R.K.; Majeed A.B.A.
Published: (2017)

Mutation analysis of BCR-ABL1 kinase domain in chronic myeloid leukemia patients with tyrosine kinase inhibitors resistance: a Malaysian cohort study
by: Seman Z.A.; Ahid F.; Kamaluddin N.R.; Sahid E.N.M.; Esa E.; Said S.S.M.; Azman N.; Mat W.K.D.W.; Abdullah J.; Ali N.A.; Khalid M.K.N.M.; Yusoff Y.M.
Published: (2024)

Mutation analysis of BCR-ABL1 kinase domain in chronic myeloid leukemia patients with tyrosine kinase inhibitors resistance: a Malaysian cohort study
by: Abu Seman, et al.
Published: (2024)

Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides
by: Kumar M.; Ramasamy K.; Mani V.; Mishra R.K.; Majeed A.B.A.; Clercq E.D.; Narasimhan B.
Published: (2014)

Synthesis and biological evaluation of heterocyclic 1,2,4-triazole scaffolds as promising pharmacological agents
by: Kumari M.; Tahlan S.; Narasimhan B.; Ramasamy K.; Lim S.M.; Shah S.A.A.; Mani V.; Kakkar S.
Published: (2021)

N-([1,1ʹ-biaryl]-4-yl)-1-naphthamide-based scaffolds synthesis, their cheminformatics analyses, and screening as bacterial biofilm inhibitor
by: Ejaz S.; Zubair M.; Rasool N.; Ahmed F.; Bilal M.; Ahmad G.; Altaf A.A.; Shah S.A.A.; Rizwan K.
Published: (2022)

4-(1-Aryl-5-chloro-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides: Synthesis, antimicrobial, anticancer evaluation and QSAR studies
by: Kumar M.; Narasimhan B.; Kumar P.; Ramasamy K.; Mani V.; Mishra R.K.; Majeed A.B.A.
Published: (2014)

Synthesis, monoamine oxidase inhibition activity and molecular docking studies of novel 4-hydroxy-N′-[benzylidene or 1-phenylethylidene]-2-H/methyl/benzyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides
by: Saddique F.A.; Zaib S.; Jalil S.; Aslam S.; Ahmad M.; Sultan S.; Naz H.; Iqbal M.; Iqbal J.
Published: (2018)

Evaluation of arbuscular mycorrhiza inoculation potential for sustainable production of aerobic rice var. MR1A
by: Baadu R.; Shamsiah A.; Joseph H.
Published: (2020)

π1a and π1b Impedance Matching for Capacitive Power Transfer System
by: Yusop Y.; Saat S.; Kamarudin K.; Husin H.; Nguang S.K.
Published: (2020)

IN VITRO EVALUATION OF SCAVENGING AND ANTI-ADIPOGENIC ACTIVITY OF Momordica Cochinchinensis (LOUR). SPRENG FRUIT EXTRACTS ON 3T3-L1 ADIPOCYTES
by: Rahman M.N.A.; Ismail A.; Azlan A.; Aziz A.F.A.; Muhammad N.H.
Published: (2024)