Synthesis, spectral analysis and biological evaluation of 2-{[(morpholin-4-yl)ethyl]thio}-5-phenyl/aryl-1,3,4-oxadiazole derivatives

Synthesis, spectral analysis and biological evaluation of 2-{[(morpholin-4-yl)ethyl]thio}-5-phenyl/aryl-1,3,4-oxadiazole derivatives

A series of new derivatives of 4-(2-chloroethyl)morpholine hydrochloride (5) were efficiently synthesized. Briefly, different aromatic organic acids (1a-f) were refluxed to acquire respective esters (2a-f) using conc. H2SO4 as catalyst. The esters were subjected to nucleophillic substitution by mono...

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Bibliographic Details
Published in:Pakistan Journal of Pharmaceutical Sciences
Main Author: Aziz-Ur-Rehman; Khan S.G.; Naqvi S.A.R.; Ahmad M.; Akhtar N.; Bokhari T.H.; Irfan M.; Usman A.; Batool S.; Rasool S.; Shah S.A.A.; Shahid M.
Format: Article
Language:English
Published: Pakistan Journal of Pharmaceutical Sciences 2021
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107334212&doi=10.36721%2fPJPS.2021.34.1.SP.441-446.1&partnerID=40&md5=e8b212439da4fd6837b001731b079baa

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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107334212&doi=10.36721%2fPJPS.2021.34.1.SP.441-446.1&partnerID=40&md5=e8b212439da4fd6837b001731b079baa

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