Synthesis and structure-activity relationship of 1-[(E)-3-phenyl-2-propenyl] piperazine derivatives as suitable antibacterial agents with mild hemolysis
A new series of 1-[(E)-3-phenyl-2-propenyl]piperazine derivatives (5a-m) as antibacterial agents was designed and synthesized. The synthetic strategy was initiated by coupling different anilines (1a-m) with bromoacetyl bromide (2) in an aqueous basic medium to acquire different electrophiles, 3a-m,...
发表在: | Scientia Iranica |
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主要作者: | |
格式: | 文件 |
语言: | English |
出版: |
Sharif University of Technology
2019
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在线阅读: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105482274&doi=10.24200%2fsci.2019.51207.2062&partnerID=40&md5=b903f115a7aea925eeacde8dff2aba0f |