Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and bsa binding studies

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Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and bsa binding studies

We synthesized a series of compounds bearing pharmacologically important 1,3,4-oxadiazole and piperidine moieties. Spectral data analysis by1H-NMR,13C-NMR, IR and EI-MS was used to elucidate the structures of the synthesized molecules. Docking studies explained the different types of interaction of...

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Bibliographic Details
Published in:	Brazilian Journal of Pharmaceutical Sciences
Main Author:	Iqbal J.; Ur-Rehman A.; Abbasi M.A.; Siddiqui S.Z.; Rasool S.; Ashraf M.; Iqbal A.; Hamid S.; Chohan T.A.; Khalid H.; Laulloo S.J.; Shah S.A.A.
Format:	Article
Language:	English
Published:	Faculdade de Ciencias Farmaceuticas (Biblioteca) 2020
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097560517&doi=10.1590%2fs2175-97902020000118092&partnerID=40&md5=100e26f6debc89a467bddf7da75347d2

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