Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and bsa binding studies
We synthesized a series of compounds bearing pharmacologically important 1,3,4-oxadiazole and piperidine moieties. Spectral data analysis by1H-NMR,13C-NMR, IR and EI-MS was used to elucidate the structures of the synthesized molecules. Docking studies explained the different types of interaction of...
Published in: | Brazilian Journal of Pharmaceutical Sciences |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Faculdade de Ciencias Farmaceuticas (Biblioteca)
2020
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097560517&doi=10.1590%2fs2175-97902020000118092&partnerID=40&md5=100e26f6debc89a467bddf7da75347d2 |