Medroxyprogesterone derivatives from microbial transformation as anti-proliferative agents and acetylcholineterase inhibitors (combined in vitro and in silico approaches)
The fungal transformations of medroxyrogesterone (1) were investigated for the first time using Cunninghamella elegans, Trichothecium roseum, and Mucor plumbeus. The metabolites obtained are as following: 6β, 20-dihydroxymedroxyprogesterone (2), 12β-hydroxymedroxyprogesterone (3), 6β, 11β-dihydroxym...
| Published in: | Steroids |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Inc.
2020
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091965702&doi=10.1016%2fj.steroids.2020.108735&partnerID=40&md5=616fb80f7c7c0626a185554a9f001331 |