Molecular docking, synthesis and biological significance of pyrimidine analogues as prospective antimicrobial and antiproliferative agents

Pyrimidine nucleus is a significant pharmacophore that exhibited excellent pharmacological activities. A series of pyrimidine scaffolds was synthesized and its chemical structures were confirmed by physicochemical and spectral analysis. The synthesized compounds were evaluated for their antimicrobia...

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Bibliographic Details
Published in:BMC Chemistry
Main Author: Kumar S.; Kaushik A.; Narasimhan B.; Shah S.A.A.; Lim S.M.; Ramasamy K.; Mani V.
Format: Article
Language:English
Published: BioMed Central Ltd 2019
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090608528&doi=10.1186%2fs13065-019-0601-z&partnerID=40&md5=333b7eb2469379dd956a3edbdc528d99