Evaluation of cytotoxic and tyrosinase inhibitory activities of 2-phenoxy(Thiomethyl) pyridotriazolopyrimidines: In vitro and molecular docking studies
Background: The use of tyrosinase has confirmed to be the best means of recognizing safe, effective, and potent tyrosinase inhibitors for whitening skin. Twenty-four 2-phenoxy(thiomethyl)pyridotriazolopyrimidines were synthesized and characterized in our previous studies. Objective: The present work...
Published in: | Anti-Cancer Agents in Medicinal Chemistry |
---|---|
Main Author: | Abuelizz H.A.; Anouar E.H.; Marzouk M.; Hasan M.H.; Saleh S.R.; Ahudhaif A.; Alburikan K.A.; Al-Salahi R. |
Format: | Article |
Language: | English |
Published: |
Bentham Science Publishers
2020
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089626979&doi=10.2174%2f1871520620666200627212128&partnerID=40&md5=e2edf0d0a7fbf7e8e6162f29ddf9b704 |
Similar Items
-
Synthesis, biological activity and molecular docking of new tricyclic series as α-glucosidase inhibitors
by: Abuelizz H.A.; Iwana N.A.N.I.; Ahmad R.; Anouar E.-H.; Marzouk M.; Al-Salahi R.
Published: (2019) -
3-Benzyl(phenethyl)-2-thioxobenzo[g]quinazolines as a new class of potent α-glucosidase inhibitors: Synthesis and molecular docking study
by: Al-Salahi R.; Ahmad R.; Anouar E.; Iwana Nor Azman N.I.; Marzouk M.; Abuelizz H.A.
Published: (2018) -
Synthesis, α-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles
by: Taha M.; Ismail N.H.; Imran S.; Mohamad M.H.; Wadood A.; Rahim F.; Saad S.M.; Rehman A.U.; Khan K.M.
Published: (2016) -
Synthesis, in vitro urease inhibitory potential and molecular docking study of Benzimidazole analogues
by: Zaman K.; Rahim F.; Taha M.; Ullah H.; Wadood A.; Nawaz M.; Khan F.; Wahab Z.; Shah S.A.A.; Rehman A.U.; Kawde A.-N.; Gollapalli M.
Published: (2019) -
Synthesis, molecular docking, dynamic simulations, kinetic mechanism, cytotoxicity evaluation of N-(substituted-phenyl)-4-{(4-[(E)-3-phenyl-2-propenyl]-1-piperazinyl} butanamides as tyrosinase and melanin inhibitors: In vitro, in vivo and in silico approaches
by: Raza H.; Abbasi M.A.; Aziz-ur-Rehman; Siddiqui S.Z.; Hassan M.; Abbas Q.; Hong H.; Shah S.A.A.; Shahid M.; Seo S.-Y.
Published: (2020)