Synthesis of halogenated [1,1′-biphenyl]-4-yl benzoate and [1,1′:3′,1″- terphenyl]-4′-yl benzoate by palladium catalyzed cascade C–C coupling and structural analysis through computational approach

QR Code

Synthesis of halogenated [1,1′-biphenyl]-4-yl benzoate and [1,1′:3′,1″- terphenyl]-4′-yl benzoate by palladium catalyzed cascade C–C coupling and structural analysis through computational approach

2,4-Dibromophenyl benzoate (3) was synthesized via Steglich esterification. The derivatives of 2, 4-dibromophenyl benzoate (3) with electron withdrawing and donating aryl-boronic acids were prepared with good yields via palladium catalyzed Suzuki Miyaura reaction. DFT calculations were also implemen...

Full description

Bibliographic Details
Published in:	Journal of Molecular Structure
Main Author:	Imran H.M.; Rasool N.; Kanwal I.; Hashmi M.A.; Altaf A.A.; Ahmed G.; Malik A.; Kausar S.; Ud-Din Khan S.; Ahmad A.; Ali Shah S.A.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2020
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087873670&doi=10.1016%2fj.molstruc.2020.128839&partnerID=40&md5=e280809431d47632017fc818342382d8

Similar Items

N-([1,1ʹ-biaryl]-4-yl)-1-naphthamide-based scaffolds synthesis, their cheminformatics analyses, and screening as bacterial biofilm inhibitor
by: Ejaz S.; Zubair M.; Rasool N.; Ahmed F.; Bilal M.; Ahmad G.; Altaf A.A.; Shah S.A.A.; Rizwan K.
Published: (2022)

Synthesis and α-glucosidase inhibition activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2h-benzo[e][1,2]thiazin-2-yl]-n-arylacetamides: An in silico and biochemical approach
by: Saddique F.A.; Aslam S.; Ahmad M.; Ashfaq U.A.; Muddassar M.; Sultan S.; Taj S.; Hussain M.; Lee D.S.; Zaki M.E.A.
Published: (2021)

4-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzohydrazide
by: Taha M.; Ismail N.H.; Imran S.; Khan K.M.
Published: (2014)

Synthesis of 2-{[5-(aralkyl/aryl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(4-methyl-1,3-thiazol-2-yl)acetamides: Novel bi-heterocycles as potential therapeutic agents
by: Ramzan M.S.; Abbasi M.A.; Aziz-Ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Ashraf M.; Lodhi M.A.; Khan F.A.; Mirza B.
Published: (2018)

Synthesis of novel N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-{[5-(un/substituted-phenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides as potent antibacterial agents
by: Abbasi M.A.; Irshad M.; Aziz-Ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Shahid M.
Published: (2022)

Synthesis, monoamine oxidase inhibition activity and molecular docking studies of novel 4-hydroxy-N′-[benzylidene or 1-phenylethylidene]-2-H/methyl/benzyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides
by: Saddique F.A.; Zaib S.; Jalil S.; Aslam S.; Ahmad M.; Sultan S.; Naz H.; Iqbal M.; Iqbal J.
Published: (2018)

Synthesis of Novel Bi-Heterocycles as Valuable Anti-Diabetic Agents: 2-({5-((2-Amino-1,3-Thiazol-4-yl)methyl)-1,3,4-Oxadiazol-2-yl}sulfanyl)-N-(Substituted)acetamides
by: Muhammad Athar Abbasi; Ramzan M.S.; Aziz-ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Lodhi M.A.; Khan F.A.; Mirza B.
Published: (2020)

Synthesis and structural analysis of persuasive antibacterial agents and enzyme inhibitors derived from 5-(1-(4-Tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol
by: Aziz-Ur-Rehman; Sattar A.; Abbasi M.A.; Siddiqui S.Z.; Raza M.A.; Ashraf M.; Nazir M.; Shah S.A.A.
Published: (2018)

Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and bsa binding studies
by: Iqbal J.; Ur-Rehman A.; Abbasi M.A.; Siddiqui S.Z.; Rasool S.; Ashraf M.; Iqbal A.; Hamid S.; Chohan T.A.; Khalid H.; Laulloo S.J.; Shah S.A.A.
Published: (2020)

N-(5-Methyl-1,3-Thiazol-2-yl)-2-{[5-((Un)Substituted- Phenyl)1,3,4-Oxadiazol-2-yl]Sulfanyl}acetamides. Unique Biheterocycles as Promising Therapeutic Agents
by: Abbasi M.A.; Ramzan M.S.; Aziz-ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Hassan M.; Seo S.-Y.; Ashraf M.; Mirza B.; Ismail H.
Published: (2018)

Synthesis, in vitro and in silico studies of novel potent urease inhibitors: N-[4-({5-[(3-Un/substituted-anilino-3-oxopropyl)sulfanyl]-1,3,4-oxadiazol-2-yl}methyl)-1,3-thiazol-2-yl]benzamides
by: Abbasi M.A.; Hassan M.; Aziz-ur-Rehman; Siddiqui S.Z.; Raza H.; Shah S.A.A.; Seo S.-Y.
Published: (2018)

Novel Bi-heterocycles as potent inhibitors of Urease and less cytotoxic agents: 3-({5-((2-amino-1,3-thiazol-4-yl)methyl)-1,3,4-oxadiazol-2-yl}sulfanyl)-N-(un/substituted-phenyl) propanamides
by: Abbasi M.A.; Ramzan M.S.; Aziz-Ur-Rehman; Siddiqui S.Z.; Hassan M.; Shah S.A.A.; Ashraf M.; Shahid M.; Seo S.-Y.
Published: (2020)

Structure–activity relationship and in silico study of unique bi-heterocycles: 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol derivatives
by: Abbasi M.A.; Ramzan M.S.; Aziz-Ur-Rehman; Siddiqui S.Z.; Hassan M.; Raza H.; Shah S.A.A.; Mirza B.; Seo S.-Y.
Published: (2019)

6-Benzyl-3-(1,4-dioxaspiro-[4.5]decan-2-yl)-8,8-dimethyl-1-oxa-2, 6-diaza-spiro-[4.4]non-2-ene-7,9-dione
by: Bathich Y.; Shaameri Z.; Hamzah A.S.; Quah C.K.; Fun H.-K.
Published: (2009)

Synthesis of new S-substituted derivatives of 5-[3-(1H-indol-3-yl) propyl]-1, 3, 4-oxadiazol-2-ylhydrosulfide as suitable antibacterial and anticancer agents with moderate cytotoxicity
by: Nazir M.; Abbasi M.A.; Aziz-Ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Shahid M.; Fatima H.; Iftikhar S.; Saleem R.S.Z.
Published: (2019)

Synthesis of some new N-substituted-N-(2,3-Dihydro-[1,4]benzodioxin-6-yl)-4-acetamidobenzenesulfonamides as valuable antibacterial agents
by: Abbasi M.A.; Tariq S.; Aziz-Ur-Rehman; Siddiqui S.Z.; Ahmad I.; Malik R.; Shah S.A.A.
Published: (2016)

Synthesis, spectral analysis and biological evaluation of 2-{[(morpholin-4-yl)ethyl]thio}-5-phenyl/aryl-1,3,4-oxadiazole derivatives
by: Aziz-Ur-Rehman; Khan S.G.; Naqvi S.A.R.; Ahmad M.; Akhtar N.; Bokhari T.H.; Irfan M.; Usman A.; Batool S.; Rasool S.; Shah S.A.A.; Shahid M.
Published: (2021)

Synthesis, molecular docking and α-glucosidase inhibition of 5-aryl-2-(6′-nitrobenzofuran-2′-yl)-1,3,4-oxadiazoles
by: Taha M.; Ismail N.H.; Imran S.; Wadood A.; Rahim F.; Saad S.M.; Khan K.M.; Nasir A.
Published: (2016)

Synthesis, Bacterial biofilm inhibition and cytotoxicity of new N-Alkyl/aralkyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-nitrobenzenesulfonamides
by: Abbasi M.A.; Zeb A.; Aziz-Ur-Rehman; Siddiqui S.Z.; Ali Shah S.A.; Shahid M.; Fatima H.
Published: (2020)

Synthesis, pharmacological screening & computational analysis of some 2-(1H-Indol-3-yl)-N'-[(un)substituted phenylmethylidene] acetohydrazides & 2-(1H-Indol-3-yl)-N'-[(un)substituted benzoyl/2-Thienylcarbonyl]acetohydrazides
by: Rubab K.; Abbasi M.A.; Aziz-Ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Ashraf M.; Qurat-Ul-Ain; Ahmad I.; Lodhi M.A.; Ghufran M.; Shahid M.; Fatima H.
Published: (2017)

Bacterial Biofilm Inhibition, Hemolytic Activity, and Structure–Activity Relationship of N-(2,3-Dihydro-1,4-Benzodioxin-6-yl)-4-Nitro-N-(Substituted-Benzyl)benzenesulfonamides
by: Muhammad A. Abbasi; Irshad M.; Aziz-ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Shahid M.
Published: (2020)

Synthesis of promising antibacterial and antifungal agents: 2-[[(4-Chlorophenyl)sulfonyl](2,3-dihydro-1,4-benzodioxin-6-yl)amino]-N(un/substituted-phenyl)acetamides
by: Abbasi M.A.; Irshad M.; Aziz-Ur-Rehman; Siddiqui S.Z.; Nazir M.; Ali Shah S.A.; Shahid M.
Published: (2020)

Design, synthesis and biological potential of 5-(2-amino-6-(3/4-bromophenyl)pyrimidin-4-yl)benzene-1,3-diol scaffolds as promising antimicrobial and anticancer agents
by: Kumar S.; Narasimhan B.; Lim S.M.; Ramasamy K.; Mani V.; Ali Shah S.A.
Published: (2019)

Crystal structure of ethyl 1-(2-hydroxyethyl)-4-((4-methoxyphenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate, C16H20N2O5
by: Abdul Rashid F.N.A.; Bacho M.Z.; Slawin A.M.Z.; Abdul Manan M.A.F.; Johari S.A.; Mohammat M.F.
Published: (2023)

Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 assimilate cholesterol and modulate ABCA1, CD36, NPC1L1 and SCARB1 in vitro
by: Lim F.T.; Lim S.M.; Ramasamy K.
Published: (2017)

Synthesis, Pharmacological Evaluation and Molecular Docking Studies of N-[2-(1H-indol-3-yl)Acetyl]Arylsulfonohydrazides
by: Rubab K.; Abbasi M.A.; Aziz-ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Ashraf M.; Qurat-ul-Ain; Lodhi M.A.; Khan F.A.; Shahid M.; Fatima H.; Ahmad I.
Published: (2021)

The implication of the polymorphisms of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease patients treated with aspirin
by: Abdul Jalil N.J.; Bannur Z.; Derahman A.; Maskon O.; Darinah N.; Hamidi H.; Ali O.; Gunasekaran; Rafizi M.; Azreen N.I.; Kek T.L.; Salleh M.Z.
Published: (2015)

Synthesis, characterization, biological evaluation and molecular docking studies of 2-(1H-benzo[d]imidazol-2-ylthio)-N-(substituted 4-oxothiazolidin-3-yl) acetamides
by: Yadav S.; Narasimhan B.; Lim S.M.; Ramasamy K.; Vasudevan M.; Shah S.A.A.; Selvaraj M.
Published: (2017)

C 1 Cubic Trigonometric Spline with a Shape Parameter for Positive Shape Preservation
by: Munir N.A.A.A.; Hadi N.A.; Nasir M.A.S.
Published: (2022)

Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4‑methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl) acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study
by: Abbasi M.A.; Riaz S.; Aziz-Ur-rehman; Siddiqui S.Z.; Shah S.A.A.; Ashraf M.; Lodhi M.A.; Khan F.A.
Published: (2019)

Biology-oriented drug synthesis (BIODS): In vitro β-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives
by: Salar U.; Khan K.M.; Taha M.; Ismail N.H.; Ali B.; Qurat-ul-Ain; Perveen S.; Ghufran M.; Wadood A.
Published: (2017)

Synthesis, β-Glucuronidase Inhibition, and Molecular Docking Studies of 1,2,4-Triazole Hydrazones
by: Jamil W.; Kumari D.; Taha M.; Khan M.N.; Baharudin M.S.; Ali M.; Kanwal M.; Lashari M.S.; Khan K.M.
Published: (2018)

Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice
by: Musa M.; Wilson K.; Sun L.; Mulay A.; Bingle L.; Marriott H.M.; LeClair E.E.; Bingle C.D.
Published: (2012)

Biology-oriented drug synthesis (BIODS) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl ether derivatives, in vitro α-amylase inhibitory activity and in silico studies
by: Taha M.; Imran S.; Ismail N.H.; Selvaraj M.; Rahim F.; Chigurupati S.; Ullah H.; Khan F.; Salar U.; Javid M.T.; Vijayabalan S.; Zaman K.; Khan K.M.
Published: (2017)

Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin
by: Teh L.K.; Langmia I.M.; Fazleen Haslinda M.H.; Ngow H.A.; Roziah M.J.; Harun R.; Zakaria Z.A.; Salleh M.Z.
Published: (2012)

A green and efficient synthetic methodology towards the synthesis of 1-allyl-6-chloro-4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives
by: Gill M.S.A.; Azzman N.; Hassan S.S.; Shah S.A.A.; Ahemad N.
Published: (2022)

Phases of LiMn1.84V0.06Ti0.1O4 cathode material
by: Zainol N.H.; Kamarulzaman N.; Osman Z.; Fadzil A.F.M.; Yahya N.F.
Published: (2017)

Palladium (0) catalyzed synthesis of thiophene based 1,3,4-oxadiazoles their reactivities and potential nonlinear optical properties
by: Abbas M.; Rizwan K.; Rasool N.; Hashmi M.A.; Ahmad G.; Rashid U.; Shah S.A.A.
Published: (2020)

Efficient Synthesis of 4-Bromo-N-(1-phenylethyl)benzamide, Arylation by Pd(0) Catalyst, Characterization and DFT Study
by: Raza Shah A.; Rasool N.; Bılal M.; Mubarık A.; Alı Hashmı M.; Nadeem Akhtar M.; Imran M.; Ahmad G.; Siddiqa A.; Adnan Alı Shah S.
Published: (2022)

Contribution of charged and polar residues for the formation of the E1-E2 heterodimer from Hepatitis C virus
by: Jusoh S.A.; Welsch C.; Siu S.W.I.; Böckmann R.A.; Helms V.
Published: (2010)