Synthesis of diindolylmethane (DIM) bearing thiadiazole derivatives as a potent urease inhibitor

The current study describes synthesis of diindolylmethane (DIM) derivatives based-thiadiazole as a new class of urease inhibitors. Diindolylmethane is natural product alkaloid reported to use in medicinal chemistry extensively. Diindolylmethane-based-thiadiazole analogs (1–18) were synthesized and c...

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Bibliographic Details
Published in:Scientific Reports
Main Author: Taha M.; Rahim F.; Khan A.A.; Anouar E.H.; Ahmed N.; Shah S.A.A.; Ibrahim M.; Zakari Z.A.
Format: Article
Language:English
Published: Nature Research 2020
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85084696332&doi=10.1038%2fs41598-020-64729-3&partnerID=40&md5=7dd36a2a0f490984a72aaffcefb69ee6