Synthesis, β-glucuronidase inhibition and molecular docking studies of cyano-substituted bisindole hydrazone hybrids
Abstract: The β-glucuronidase, a lysosomal enzyme, catalyzes the cleavage of glucuronosyl-O-bonds. Its inhibitors play a significant role in different medicinal therapies as they cause a decrease in carcinogen-induced colonic tumors by reducing the level of toxic substances present in the intestine....
| Published in: | Molecular Diversity |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media Deutschland GmbH
2021
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083494465&doi=10.1007%2fs11030-020-10084-4&partnerID=40&md5=1a1f9de60075778928939203e78caf38 |