Aryl-oxadiazole Schiff bases: Synthesis, α-glucosidase in vitro inhibitory activity and their in silico studies

α-Glucosidase enzyme is a therapeutic target for diabetes mellitus and its inhibitors play a vital role in the treatment of this disease. A new series of aryl-oxadiazole Schiff bases (1–18) were synthesized and evaluated for α-glucosidase inhibitory potential. Fifteen compounds 1–8, 11–13, and 15–18...

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Bibliographic Details
Published in:Arabian Journal of Chemistry
Main Author: Ullah H.; Rahim F.; Taha M.; Hussain R.; Tabassum N.; Wadood A.; Nawaz M.; Mosaddik A.; Imran S.; Wahab Z.; Miana G.A.; Kanwal; Khan K.M.
Format: Article
Language:English
Published: Elsevier B.V. 2020
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079635932&doi=10.1016%2fj.arabjc.2020.01.005&partnerID=40&md5=2c10960541d3907fc7c5d0bc937fb974