Computational approaches: Discovery of GTPase HRas as prospective drug target for 1,3-diazine scaffolds

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Computational approaches: Discovery of GTPase HRas as prospective drug target for 1,3-diazine scaffolds

Heterocyclic 1,3-diazine nucleus is a valuable pharmacophore in the field of medicinal chemistry and exhibit a wide spectrum of biological activities. PharmMapper, a robust online tool used for establishing the target proteins based on reverse pharmacophore mapping. PharmMapper study is carried out...

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Bibliographic Details
Published in:	BMC Chemistry
Main Author:	Kumar S.; Sharma D.; Narasimhan B.; Ramasamy K.; Shah S.A.A.; Lim S.M.; Mani V.
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2019
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077108304&doi=10.1186%2fs13065-019-0613-8&partnerID=40&md5=4a6692550e891a186ab1ee1e0c1119e9

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