Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study

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Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study

Here in this study regarding the over expression of TP, which causes some physical, mental and socio problems like psoriasis, chronic inflammatory disease, tumor angiogenesis and rheumatoid arthritis etc. By this consideration, the inhibition of this enzyme is vital to secure life from serious threa...

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Bibliographic Details
Published in:	Scientific Reports
Main Author:	Zaman K.; Rahim F.; Taha M.; Wadood A.; Shah S.A.A.; Ahmed Q.U.; Zakaria Z.A.
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074621583&doi=10.1038%2fs41598-019-52100-0&partnerID=40&md5=8b9ce6834ce52fcfe124b7a656424354

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