QR Code

Effects of proton pump inhibitor on the human gut microbiome profile in multi-ethnic groups in Singapore

INTRODUCTION The objectives of this study were to examine the effects of ethnicity, gender and a proton pump inhibitor (PPI), omeprazole, on the human gut microbiome. PPIs are commonly used for the treatment of acid-related disorders. We hypothesised that PPI therapy might perturb microbial communit...

Full description

Bibliographic Details
Published in:	Singapore Medical Journal
Main Author:	Koo S.H.; Deng J.; Ang D.S.W.; Hsiang J.C.; Lee L.S.; Aazmi S.; Mohamed E.H.M.; Yang H.; Yap S.Y.; Teh L.K.; Salleh M.Z.; Lee E.J.D.; Ang T.L.
Format:	Article
Language:	English
Published:	Singapore Medical Association 2019
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074227747&doi=10.11622%2fsmedj.2018152&partnerID=40&md5=645033618660ff99a4cf9f2cdd67a9e8

Similar Items

The Design and Evaluation of ‘MoM (Microbiome of Maternity)’ Role-Playing Game (RPG) in Educating on the Importance of Diet and Lifestyle and Its Interactions with the Gut Microbiota During Pregnancy
by: Ismail M.I.; Aazmi S.; Nazamuddin A.; Joseph S.N.R.A.; Hamid S.B.A.; Abdullah B.; Daud S.
Published: (2022)

Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin
by: Moayyedi P.; Eikelboom J.W.; Bosch J.; Connolly S.J.; Dyal L.; Shestakovska O.; Leong D.; Anand S.S.; Störk S.; Branch K.R.H.; Bhatt D.L.; Verhamme P.B.; O'Donnell M.; Maggioni A.P.; Lonn E.M.; Piegas L.S.; Ertl G.; Keltai M.; Bruns N.C.; Muehlhofer E.; Dagenais G.R.; Kim J.-H.; Hori M.; Steg P.G.; Hart R.G.; Diaz R.; Alings M.; Widimsky P.; Avezum A.; Probstfield J.; Zhu J.; Liang Y.; Lopez-Jaramillo P.; Kakkar A.K.; Parkhomenko A.N.; Ryden L.; Pogosova N.; Dans A.L.; Lanas F.; Commerford P.J.; Torp-Pedersen C.; Guzik T.J.; Vinereanu D.; Tonkin A.M.; Lewis B.S.; Felix C.; Yusoff K.; Metsarinne K.P.; Fox K.A.A.; Yusuf S.
Published: (2019)

Coffee consumption revealed sex differences in host endogenous metabolism and gut microbiota in healthy adults
by: Chong C.W.; Wong L.C.; Teh C.S.J.; Ismail N.H.; Chan P.Q.; Lim C.S.; Yap S.C.; Yap I.K.S.
Published: (2020)

Ascaris lumbricoides harbors a distinct gut microbiota profile from its human host: Preliminary insights
by: Muslim A.; Aazmi S.; Er Y.X.; Shahrizal S.; Lim Y.A.L.
Published: (2024)

Research open access fine-scale population structure of Malays in peninsular Malaysia and Singapore and implications for association studies
by: Hoh B.-P.; Deng L.; Julia-Ashazila M.J.; Zuraihan Z.; Nur-Hasnah M.; Nur-Shafawati A.R.; Hatin W.I.; Endom I.; Zilfalil B.A.; Khalid Y.; Xu S.
Published: (2015)

Gut microbiota in pregnant Malaysian women: a comparison between trimesters, body mass index and gestational diabetes status
by: Abdullah B.; Daud S.; Aazmi M.S.; Idorus M.Y.; Mahamooth M.I.J.
Published: (2022)

Single step PCR for detection of allelic variation of MDR1 gene (P-glycoprotein) among three ethnic groups in Malaysia
by: Teh L.K.; Lee W.L.; Amir J.; Salleh M.Z.; Ismail R.
Published: (2007)

Gut Microbiota Profiles in Myopes and Nonmyopes
by: Omar W.E.W.; Singh G.; McBain A.J.; Cruickshank F.; Radhakrishnan H.
Published: (2024)

Ascaris lumbricoides harbors a distinct gut microbiota profile from its human host: Preliminary insights
by: Muslim, et al.
Published: (2024)

Effects of Extraction Methods on Phenolic Content in the Young Bamboo Culm Extracts of Bambusa beecheyana Munro
by: Nuzul M.I.; Jong V.Y.M.; Koo L.F.; Chan T.H.; Ang C.H.; Idris J.; Husen R.; Wong S.W.
Published: (2022)

Academic leadership qualities towards innovation endeavours in an organisation: A comparative study of Malaysia and Singapore perceptions
by: Quah C.S.; Sim S.P.L.; Tan W.-L.
Published: (2021)

Design and sizing water pumping system powered by photovoltaic
by: Arifin A.I.M.; Redzuan F.N.M.; Kadir E.A.; Ismail N.; Zain M.F.M.
Published: (2020)

Assessment of Subgrade Degradation Induced Mud Pumping at Railway Track: A Review
by: Yahaya N.N.; Ibrahim A.; Ahmad J.; Ahmad A.; Rozli M.I.F.; Ramli Z.
Published: (2022)

Enhancing protonic ceramic fuel cell performance through nanomilling of BCZY electrolyte powder
by: Cheng, et al.
Published: (2023)

In vivo proton magnetic resonance spectroscopy (1H-MRS) evaluation of the metabolite concentration of optic radiation in primary open angle glaucoma
by: Sidek S.; Ramli N.; Rahmat K.; Ramli N.M.; Abdulrahman F.; Kuo T.L.
Published: (2016)

Does foreign direct investment successfully lead to sustainable development in Singapore?
by: Ridzuan A.R.; Ismail N.A.; Hamat A.F.C.
Published: (2017)

Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians
by: Muthiah Y.D.; Lee W.L.; Teh L.K.; Ong C.E.; Ismail R.
Published: (2005)

A Review of Solid-State Proton–Polymer Batteries: Materials and Characterizations
by: Rani M.S.A.; Norrrahim M.N.F.; Knight V.F.; Nurazzi N.M.; Abdan K.; Lee S.H.
Published: (2023)

Predictive Maintenance of Produced Water Re-injection Pump Failure in the Field of Oil and Gas: A Review
by: Azrag M.A.K.; Khatir S.K.; Zain J.M.; Odili J.B.
Published: (2023)

EXPLORING MEDICAL TOURISM COMPETITIVENESS IN MALAYSIA, THAILAND, AND SINGAPORE: THE INDONESIAN TOURISTS’ PERSPECTIVES
by: Md Zain N.A.; Hanafiah M.H.; Asyraff M.A.; Ismail H.; Wan Mohd Zain W.M.A.
Published: (2023)

The state of food security: A comparative study between Malaysia, Singapore, and Indonesia
by: Sukereman A.S.; Ab Rahim N.; Zainol N.N.; Azmi N.A.; Nordin M.S.A.
Published: (2022)

The Philippines' and Singapore's journeys towards liberalised electricity supply industries - Takeaways for Malaysia
by: Aris H.; Mohd Zawawi I.S.; Jørgensen B.N.
Published: (2020)

Effects of non-pharmacological interventions on gut microbiota and intestinal permeability in older adults: A systematic review: Non-pharmacological interventions on gut microbiota/barrier
by: Hairul Hisham H.I.; Lim S.M.; Neoh C.F.; Abdul Majeed A.B.; Shahar S.; Ramasamy K.
Published: (2025)

Chetti Malacca: exploring millennials consumption intention of Peranakan Indian ethnic cuisine
by: Ismail M.J.; Abdul Latip M.S.
Published: (2024)

Numerical Modelling of a Valveless Impedance Pump with Various Pinch Locations
by: Mahat M.M.; Jamali M.S.A.; Kasolang S.
Published: (2022)

Purchase Behaviour Towards Proton and Perodua Cars in Malaysia: A Preliminary Study of the What and Why
by: Weng J.T.; Wun M.K.S.; Hock R.L.T.; Kasuma J.; Palaneeswaran E.; Panarina E.
Published: (2023)

Techno economic analysis of PV pumping system for rural village in East Java
by: Aripriharta; Putri D.A.; Wibawa A.P.; Sujito; Bagaskoro M.C.; Omar S.
Published: (2024)

Investigation of breast cancer molecular subtype in a multi-ethnic population using MRI
by: Mumin N.A.; Ramli Hamid M.T.; Ding Wong J.H.; Chiew S.-F.; Rahmat K.; Ng K.H.
Published: (2024)

Binding sites of deprotonated citric acid and ethylenediaminetetraacetic acid in the chelation with Ba2+, Y3+, and Zr4+ and their electronic properties: A density functional theory study
by: Abdullah N.A.F.; Ang L.S.
Published: (2018)

Comparative Analysis of MFCC and Mel-Spectrogram Features in Pump Fault Detection Using Autoencoder
by: Bin Saharom A.S.; Ehara F.
Published: (2024)

Influence of AEM Model on the Sustainable Development of Traditional Ethnic Handicraft
by: Xian, et al.
Published: (2023)

The physical and cultural attributes of ethnic enclave: A basis for conservation
by: Bakri A.F.; Qamaruz Zaman N.; Kamarudin H.; Mohd Dom M.; Alias Z.
Published: (2014)

The influence of biculturalism/integration attributes on ethnic food identity formation
by: Ishak N.; Zahari M.S.M.; Talib S.A.; Hanafiah H.M.
Published: (2019)

Basis Set Effects on the Stabilities and Interaction Energies of Small Amide Molecules Adsorbed on Kaolinite Surface
by: Nabil N.-A.M.; Ang L.S.; Sulaiman S.
Published: (2023)

Diagnostic Efficacy of Synthesized 2D Digital Breast Tomosynthesis in Multi-ethnic Malaysian Population
by: Mumin N.A.; Rahmat K.; Fadzli F.; Ramli M.T.; Westerhout C.J.; Ramli N.; Rozalli F.I.; Ng K.H.
Published: (2019)

Transient performance simulation and technoeconomic assessment of a smart building energy plant driven by solar energy coupled to a reversible heat pump
by: Hai T.; Liu Y.; Zhou J.; Li S.; Zain J.M.; Yusoff M.; Ben Moussa S.; Abd El-Gawad H.H.
Published: (2023)

Unveiling the Gut Microbiota of Pig-Tailed Macaque (Macaca nemestrina) in Selected Habitats in Malaysia
by: Osman N.; Gani M.; Tingga R.; Abdul-Latiff M.; Mohd-Ridwan A.; Chan E.; Md-Zain B.
Published: (2024)

Subjective and Objective Needs Analysis of Mandarin Learners
by: LAM K.C.; ANG L.H.; HOE F.T.; TING H.L.
Published: (2023)

Effects of polarization function on the spin contamination and distribution in β'-me4p[pd(Dmit)2]2
by: Ahmad S.N.A.; Sulaiman S.; Ang L.S.; Watanabe I.
Published: (2019)

Genetic relatedness of indigenous ethnic groups in northern Borneo to neighboring populations from Southeast Asia, as inferred from genome-wide SNP data
by: Yew C.W.; Hoque M.Z.; Pugh-Kitingan J.; Minsong A.; Voo C.L.Y.; Ransangan J.; Lau S.T.Y.; Wang X.; Saw W.Y.; Ong R.T.-H.; Teo Y.-Y.; Xu S.; Hoh B.-P.; Phipps M.E.; Kumar S.V.
Published: (2018)