Synthesis, α-amylase inhibition and molecular docking study of bisindolylmethane sulfonamide derivatives

We have synthesized nineteen (1–19) bisindolylmethane sulfonamide analogs, characterized by different spectroscopic techniques such as 1HNMR and EI-MS and tested for α-amylase inhibitory potential. All compounds showed excellent to moderate degree of α-amylase inhibitory potential with IC50 values r...

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Bibliographic Details
Published in:Medicinal Chemistry Research
Main Author: Taha M.; Noreen T.; Imran S.; Nawaz F.; Chigurupati S.; Selvaraj M.; Rahim F.; Hadiani Ismail N.; Kumar A.; Mosaddik A.; Alghamdi A.M.; Abdulrahman nasser alqahtani Y.; Abdulrahman nasser alqahtani A.
Format: Article
Language:English
Published: Birkhauser Boston 2019
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071757214&doi=10.1007%2fs00044-019-02431-4&partnerID=40&md5=93c0f889f68b704a14359e94b957c2eb