Synthesis, α-amylase inhibition and molecular docking study of bisindolylmethane sulfonamide derivatives
We have synthesized nineteen (1–19) bisindolylmethane sulfonamide analogs, characterized by different spectroscopic techniques such as 1HNMR and EI-MS and tested for α-amylase inhibitory potential. All compounds showed excellent to moderate degree of α-amylase inhibitory potential with IC50 values r...
Published in: | Medicinal Chemistry Research |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Birkhauser Boston
2019
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071757214&doi=10.1007%2fs00044-019-02431-4&partnerID=40&md5=93c0f889f68b704a14359e94b957c2eb |