| Summary: | Meconium Aspiration Syndrome (MAS) is a disorder affecting the infants who born with meconium stained amniotic fluid causing significant morbidity & mortality. Post-term infants are affected more. Thick meconium and birth asphyxia are important risk factors. In severe cases, development of pulmonary hypertension is common. In vigorous infants’ endotracheal intubation and suctioning are not effective & in non-breathing infants these are controversial. The treatment modalities include oxygen therapy, mechanical ventilation, and nitric oxide inhalation. Infants with severe parenchymal involvement are benefited by surfactant. In some cases, Extracorporeal Membrane Oxygenation (ECMO) & high-frequency ventilation are considered. © 2019 Lahore Medical And Dental College. All rights reserved.
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