Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]

Chemical constituents and biological activities of the aerial parts of Piper erecticaule C.DC. have been studied for the first time. Fractionation and purification of the extracts afforded aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4), piperolactam D (5), togethe...

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Published in:	Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas
Main Author:	Salleh W.M.N.H.W.; Abdullah N.; Hashim N.A.; Khong H.Y.; Khamis S.
Format:	Article
Language:	English
Published:	Universidad de Santiago de Chile 2019
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071610033&doi=10.35588%2fblacpma.19.18.5.35&partnerID=40&md5=3ba086f363d823a98a4f4386cc8ef40b

id	2-s2.0-85071610033
spelling	2-s2.0-85071610033 Salleh W.M.N.H.W.; Abdullah N.; Hashim N.A.; Khong H.Y.; Khamis S. Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa] 2019 Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 18 5 10.35588/blacpma.19.18.5.35 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071610033&doi=10.35588%2fblacpma.19.18.5.35&partnerID=40&md5=3ba086f363d823a98a4f4386cc8ef40b Chemical constituents and biological activities of the aerial parts of Piper erecticaule C.DC. have been studied for the first time. Fractionation and purification of the extracts afforded aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4), piperolactam D (5), together with terpenoids of β-sitosterol, β-sitostenone, taraxerol, and lupeol. The structures of these compounds were obtained by analysis of their spectroscopic data, as well as the comparison with that of reported data. Acetylcholinesterase inhibitory activity revealed that compounds 1 and 3 showed strong AChE inhibitory effects with the percentage inhibition of 75.8% and 74.8%, respectively. © 2019, Universidad de Santiago de Chile. All rights reserved. Universidad de Santiago de Chile 7177917 English Article All Open Access; Gold Open Access
author	Salleh W.M.N.H.W.; Abdullah N.; Hashim N.A.; Khong H.Y.; Khamis S.
spellingShingle	Salleh W.M.N.H.W.; Abdullah N.; Hashim N.A.; Khong H.Y.; Khamis S. Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]
author_facet	Salleh W.M.N.H.W.; Abdullah N.; Hashim N.A.; Khong H.Y.; Khamis S.
author_sort	Salleh W.M.N.H.W.; Abdullah N.; Hashim N.A.; Khong H.Y.; Khamis S.
title	Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]
title_short	Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]
title_full	Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]
title_fullStr	Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]
title_full_unstemmed	Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]
title_sort	Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]
publishDate	2019
container_title	Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas
container_volume	18
container_issue	5
doi_str_mv	10.35588/blacpma.19.18.5.35
url	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071610033&doi=10.35588%2fblacpma.19.18.5.35&partnerID=40&md5=3ba086f363d823a98a4f4386cc8ef40b
description	Chemical constituents and biological activities of the aerial parts of Piper erecticaule C.DC. have been studied for the first time. Fractionation and purification of the extracts afforded aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4), piperolactam D (5), together with terpenoids of β-sitosterol, β-sitostenone, taraxerol, and lupeol. The structures of these compounds were obtained by analysis of their spectroscopic data, as well as the comparison with that of reported data. Acetylcholinesterase inhibitory activity revealed that compounds 1 and 3 showed strong AChE inhibitory effects with the percentage inhibition of 75.8% and 74.8%, respectively. © 2019, Universidad de Santiago de Chile. All rights reserved.
publisher	Universidad de Santiago de Chile
issn	7177917
language	English
format	Article
accesstype	All Open Access; Gold Open Access
record_format	scopus
collection	Scopus
_version_	1809677905451548672

Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]

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