Aporphine alkaloids from piper erecticaule and acetylcholinesterase inhibitory activity; [Alcaloides de aporfina obtenida de piper erecticaule y actividad inhibitoria de la acetilcolinesterasa]
Chemical constituents and biological activities of the aerial parts of Piper erecticaule C.DC. have been studied for the first time. Fractionation and purification of the extracts afforded aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4), piperolactam D (5), togethe...
| Published in: | Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Universidad de Santiago de Chile
2019
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071610033&doi=10.35588%2fblacpma.19.18.5.35&partnerID=40&md5=3ba086f363d823a98a4f4386cc8ef40b |
| Summary: | Chemical constituents and biological activities of the aerial parts of Piper erecticaule C.DC. have been studied for the first time. Fractionation and purification of the extracts afforded aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4), piperolactam D (5), together with terpenoids of β-sitosterol, β-sitostenone, taraxerol, and lupeol. The structures of these compounds were obtained by analysis of their spectroscopic data, as well as the comparison with that of reported data. Acetylcholinesterase inhibitory activity revealed that compounds 1 and 3 showed strong AChE inhibitory effects with the percentage inhibition of 75.8% and 74.8%, respectively. © 2019, Universidad de Santiago de Chile. All rights reserved. |
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| ISSN: | 7177917 |
| DOI: | 10.35588/blacpma.19.18.5.35 |